SKU: 51301118374

FOXP3 Recombinant Mouse mAb, PBS Only (SDT-3494)

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Description

FOXP3 Recombinant Mouse mAb, PBS Only (SDT-3494)Product Specification Host Mouse Antigen FOXP3 Synonyms Forkhead box protein P3; Scurfin; IPEX Location Cytoplasm, Nucleus Accession Q9BZS1 Clone Number SDT 3494 Antibody Type Mouse mAb Isotype IgG1,k Application WB, IHC P Reactivity Hu, Ms, Rt Positive Sample mouse heart Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt reconstitution,

Product Specification


Host Mouse
Antigen FOXP3
Synonyms Forkhead box protein P3; Scurfin; IPEX
Location Cytoplasm, Nucleus
Accession Q9BZS1
Clone Number SDT-3494
Antibody Type Mouse mAb
Isotype IgG1,k
Application WB, IHC-P
Reactivity Hu, Ms, Rt
Positive Sample mouse heart
Purification Protein G
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS
Stability & Storage

12 months from date of receipt / reconstitution, 4 °C as supplied

Dilution


application dilution species
WB 1:1000 Ms
IHC-P 1:250-1:1000 Hu, Ms, Rt

Background

FOXP3 protein is a crucial transcription factor that plays a central role in the development and function of regulatory T cells (Tregs), which are essential for maintaining immune tolerance and preventing autoimmune diseases. It is predominantly expressed in Tregs and helps suppress the activity of other immune cells, thereby preventing excessive immune responses. Mutations or dysfunction in the FOXP3 gene can lead to severe autoimmune disorders such as IPEX syndrome, highlighting its importance in immune regulation. Additionally, FOXP3 has been implicated in various other biological processes, including cancer immunology, where its expression in tumor-infiltrating Tregs can influence the tumor microenvironment and affect the efficacy of immunotherapies.

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Exchange/Return Notes
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SKU: 51301118374

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4.2 ★★★★★
Based on 8 reviews
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J
Verified Purchase
Jamie Liverseed
Natrona Heights, US
★★★★★ 5
Very durable!
Color: Blue T-Bone, Size: 1 Count
Great product! Dogs love it and very durable. I had been buying the nylon bones in pack of 3, but my 2 dogs would chew them up in no time, and I was buying the aggressive chewer bones. Bought 2 of these, dogs loved it, so I bought another one. Have had these for about 2- 2 1/2 months and still holding up just fine. And the price is great! Would definitely recommend!
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Reviewed in the United States on May 5, 2026
J
Verified Purchase
joyce rutledge
Natrona Heights, US
★★★★★ 5
Boston Terrier love
Color: Blue T-Bone, Size: 1 Count
My baby loves this chew toy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 9, 2026
K
Verified Purchase
Kristina Lee Harris-Osborne
Boise, US
★★★★★ 5
Best toys ever
Color: Blue T-Bone, Size: 2 Count
Some of the best toys ever. Last a long time for my Frenchies.
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Reviewed in the United States on May 15, 2026
T
Verified Purchase
Tracy Vargas
Boise, US
★★★★★ 4
Great for chewing but very sharp and mangled in a few days
Color: Blue Gator, Size: 1 Count, Color: Blue Gator, Size: 1 Count
I thought this was a fantastic idea having baking soda added for fresh clean teeth while enjoying a new toy. I wanted to review 2 main things about this. First, if my dog enjoyed this toy. That answer would be yes absolutely! She is chewing it as I’m writing this right now. She can spend a good amount of time chewing away on this and it keeps her busy without having to use a rawhide treat which we only try to use if we re going to be gone for longer then 4 hours. The kids love playing fetch with her and she stays engaged the whole time. It is very heavy and when being thrown can become a weapon so I always supervise! Last, the durability of the toy. So it is durable but not completely. As you can see the toy got very sharp where she has been chewing it and I’ve even noticed a little blood on it which means it’s cutting her gums. It wasn’t a large enough amount for me to take it away. It is still almost the exact same size but maybe after a month I will re edit this for more accurate on durability since it’s only been about a week that she has gotten it. Overall, I would recommend this toy it’s a great price and keeps her attention a lot more then other toys I spent twice the amount of money on!
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Reviewed in the United States on March 9, 2022
C
Verified Purchase
CoCo
Battle Creek, US
★★★★★ 3
Too Hard
Color: Blue T-Bone, Size: 1 Count
I have a pit puppy, 20 lbs, who loves to chew. She's huge for her age, and I wanted to get her a new toy. I bought two different toys, hoping she would like one. The other toy was a hit, they both jumped at it and were excited about it, probably because it had rawhide rings that went with it. This one was immediately thrown to the side, even though my pit loves to chew on non edible toys. I think this one was just too hard, because both her, and my Chihuahua-Jack Russell, weren't interested. It didn't have any smell to attract them, which is why I bought it, because they love peanut butter stuff. I'm not going to go as far as to lick it and taste it... I'm pretty sure it won't taste like peanut butter, either. I feel so bad for my little pittie, she's just sitting here with a sad look on her face because my other dog stole the fun chew toy. I've immediately ordered another of one of those so they both have one, but I've just money wasted on this one. It's probably better they don't like it, I'd be worried about them breaking their teeth. I know it's supposed to be for power chewers, but it has no give whatsoever, just extremely hard, shiny plastic. It's useless, unless you're planning on filing it into a point and making a prison shank. Maybe you can leave it in front of the fridge for your SO to step on in the middle of the night when he goes to steal your almond milk. I'll figure out some way to use it. I did dip it into my boyfriend's peanut butter jar to let my puppy lick it, but I can do that with a spoon. I wanted her to feel like she got something, maybe my other dog will let her have a turn with the fun toy after awhile. That's the only reason I gave it 3 stars. You can dip it in peanut butter and I was being generous.
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Reviewed in the United States on March 27, 2022

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