Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 31 - Sep 5
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Pex14 Recombinant Rabbit mAb (S-2379-8)Product Specification Host Rabbit Antigen Pex14 Synonyms Peroxisomal membrane protein PEX14; PTS1 receptor docking protein; Peroxin 14; Peroxisomal membrane anchor protein PEX14; PEX14 Immunogen Synthetic Peptide Accession O75381 Clone Number S 2379 8 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu Positive Sample Raji, A431, HeLa, 293T, HepG2 Purification Protein A Concentration 2 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | Pex14 |
| Synonyms | Peroxisomal membrane protein PEX14; PTS1 receptor-docking protein; Peroxin-14; Peroxisomal membrane anchor protein PEX14; PEX14 |
| Immunogen | Synthetic Peptide |
| Accession | O75381 |
| Clone Number | S-2379-8 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Positive Sample | Raji, A431, HeLa, 293T, HepG2 |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| IHC-P | 1:100 | Hu |
| ICC | 1:50 | Hu |
Background
PEX14, encoded by the PEX14 gene, is an integral peroxisomal membrane protein whose C-terminus faces the cytosol and constitutes the docking site for the PTS1 receptor PEX5 (and, indirectly, the PTS2 receptor PEX7), thereby nucleating the PEX13-PEX14 translocon pore that imports peroxisomal matrix proteins; beyond its essential role in peroxisome biogenesis, PEX14 also binds microtubules to drive organelle motility, functions as a transcriptional corepressor by recruiting histone deacetylases, and—uniquely among peroxins—is strictly required for selective autophagic degradation of peroxisomes (pexophagy), while mutations in PEX14 produce a Zellweger-syndrome phenotype .
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy