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Description
Alexa Fluor® 647 Mouse Anti-Human CD166 Antibody (S-2869)Product Specification Host Mouse Antigen CD166 Synonyms CD166 antigen; Activated leukocyte cell adhesion molecule; MEMD; ALCAM Location Cell membrane Accession Q13740 Clone Number S 2869 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin
Product Specification
| Host | Mouse |
| Antigen | CD166 |
| Synonyms | CD166 antigen; Activated leukocyte cell adhesion molecule; MEMD; ALCAM |
| Location | Cell membrane |
| Accession | Q13740 |
| Clone Number | S-2869 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood |
| Purification | Protein G |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1.25μl per million cells in 100μl volume | Hu |
Background
CD166, also known as Activated Leukocyte Cell Adhesion Molecule (ALCAM), is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. It is encoded by the ALCAM gene and is involved in both homotypic and heterotypic cell adhesion. CD166 is expressed on various cell types, including activated T cells, epithelial cells, fibroblasts, and neurons. It plays a crucial role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during T cell development. Additionally, CD166 is overexpressed in several types of tumors and serves as a potential cancer stem cell marker, making it a target for cancer research and therapy.
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