Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 28 - Sep 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Armenian hamster Anti-Mouse CD48 Antibody (S-R654)Product Specification Host Armenian hamster Antigen Mouse CD48 Synonyms CD48 antigen; BCM1 surface antigen; BLAST 1; HM48 1; MRC OX 45 surface antigen; SLAM family member 2 (SLAMF2); Signaling lymphocytic activation molecule 2; sgp 60; Bcm 1 Location Cell membrane Accession P18181 Clone Number S R654 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 2
Product Specification
| Host | Armenian hamster |
| Antigen | Mouse CD48 |
| Synonyms | CD48 antigen; BCM1 surface antigen; BLAST-1; HM48-1; MRC OX-45 surface antigen; SLAM family member 2 (SLAMF2); Signaling lymphocytic activation molecule 2; sgp-60; Bcm-1 |
| Location | Cell membrane |
| Accession | P18181 |
| Clone Number | S-R654 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:2000 | Ms |
Background
CD48 (also known as SLAMF2) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein and a member of the signaling lymphocyte activation molecule (SLAM) family. It is expressed on various immune cells, including T cells, B cells, and natural killer (NK) cells. CD48 interacts with several ligands, such as CD2 and CD244 (2B4), to mediate immune cell adhesion, activation, and signaling. These interactions play crucial roles in T cell activation, NK cell cytotoxicity, and immune synapse formation. In disease contexts, CD48 expression is often upregulated in inflammatory conditions and certain cancers, such as acute myeloid leukemia (AML), where it may influence immune evasion and tumor progression. Additionally, CD48 has been identified as a potential biomarker and therapeutic target in autoimmune diseases, allergic conditions, and cancer immunotherapy.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy