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Description
TCL1 Recombinant Rabbit mAb(SDT-052-12)Product Specification Host Rabbit Antigen TCL1 Synonyms Oncogene TCL 1, Protein p14 TCL1 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus Accession P56279 Clone Number SDT 052 12 Antibody Type Rabbit mAb Application WB, IHC P, IP Reactivity Hu Purification Protein A Concentration 0. 5mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date
Product Specification
| Host | Rabbit |
| Antigen | TCL1 |
| Synonyms | Oncogene TCL-1, Protein p14 TCL1 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus |
| Accession | P56279 |
| Clone Number | SDT-052-12 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, IP |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.5mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | |
| WB | 1:1000 | |
| IP | 1:25 |
Background
T-cell leukemia/lymphoma protein 1A is a protein that in humans is encoded by the TCL1A gene. The TCL1 locus on human chromosome 14q32.1 is activated in T-cell leukemias by translocations and inversions that juxtapose it to regulatory elements of T-cell receptor genes. TCL1A has been shown to interact with AKT1 and AKT2. Protein expression in immature T and B lymphoid cells and overexpression of TCL1 is considered critical in the oncogenetic transformation.
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