SKU: 62219689850

MICA/MICB Recombinant Rabbit mAb (S-1589-10)

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Description

MICA/MICB Recombinant Rabbit mAb (S-1589-10)Product Specification Host Rabbit Antigen MICA MICB Synonyms MHC class I polypeptide related sequence A; MIC A; PERB11. 1; Immunogen Recombinant Protein Location Cytoplasm, Cell membrane, Endoplasmic reticulum Accession Q29983 Q29980 Clone Number S 1589 10 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample HCT 116, HeLa, A431, MCF7, HUVEC Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated

Product Specification


Host Rabbit
Antigen MICA/MICB
Synonyms MHC class I polypeptide-related sequence A; MIC-A; PERB11.1;
Immunogen Recombinant Protein
Location Cytoplasm, Cell membrane, Endoplasmic reticulum
Accession Q29983、 Q29980
Clone Number S-1589-10
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample HCT 116, HeLa, A431, MCF7, HUVEC
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu

Background

MICA (MHC class I polypeptide-related sequence A) and MICB (MHC class I polypeptide-related sequence B) are stress-inducible proteins that belong to the MHC class I family but do not bind to β2-microglobulin or present peptides. They are encoded by genes located within the HLA class I region of chromosome 6. MICA and MICB are expressed on the cell membrane in response to cellular stress or cancer transformation. These proteins act as ligands for the NKG2D receptor, which is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells. The binding of MICA/B to NKG2D can activate these immune cells, leading to cytotoxic responses against stressed or transformed cells. MICA and MICB are highly polymorphic, with over 106 alleles reported for MICA and 25 for MICB. This polymorphism may affect their affinity for NKG2D and, consequently, the activation thresholds of NK and T cells.

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SKU: 62219689850

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Kindle Customer
Massapequa, US
★★★★★ 5
Exelente
Format: Paperback
Exelente
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Reviewed in the United States on March 27, 2026
A
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Adel Awadallah
Carnegie, US
★★★★★ 5
Great.
Format: Paperback
Easy to follow and understand.
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Reviewed in the United States on April 13, 2025
A
A. Stallings
Belleville, US
★★★★★ 4
Really enjoy the book and understanding
Format: Paperback
I can't speak for other people and their experience on the book. But installing MySQL wasn't a problem for me following the book instructions and the instructions from the actual Oracle site. Afterwards I relished each of the sessions of segments to learn. Creating tables and then pulling up specifics from that table to access. Or just running the whole table. I took notes for each of the sections as well. I do recommend saving not deleting the tables you do in the sections. So that way one can go back to those table and play around with it. I also recommend tweaking the data to your liking and change it up to be creatively fun. Learning is fun if U can squeeze it in to make it.
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Reviewed in the United States on June 30, 2022
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N. Vadulam
Omaha, US
★★★★★ 1
Not Good at ALL !!
Format: Paperback
This book on SQL is disappointing! It is awful even at the beginning. First of all, you must install MySQL to practice SQL! The author barely skims over this important step! Without properly installing My SQL, you cannot do the rest of the stuff in this book. I am sorry, I tried and failed in following this book.
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Reviewed in the United States on October 27, 2021
F
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faith
Houston, US
★★★★★ 5
A small book but a true gem!
Format: Paperback, Format: Paperback
Max Lucado’s “God Will Use This for Good” is an excellent book that I highly recommend. It’s only 47 pages but the words carry a very strong message for those of us who feel helplessness in our lives. I purchased it because it’s a feeling I have. This book has reminded me time & time again, as I remember what I’ve read or I reread it. It’s an easy read. The book begins with a prayer which I included pictures of. There are 4 short chapters that follow, a response page & finally with uplifting scriptures. The focus of the book is on Joseph, the Son of Jacob. His story is told in the Bible. His Father adored him above his Brothers which in turn made his Brothers hate him. They hated him so much they threw him in a pit they were certain he would die in. Mr. Lucado writes this book with the focus on strength Joseph had to endure 20 years in this pit, as written in the Bible. At the age of 37 he became much more than a 17yo boy thrown in a bottomless pit. Why? He believed. This story is reflected onto us who face dark days. Mr. Lucado writes that God will get us THROUGH these times. THROUGH is a common word in many scriptures. It’s further written that “You’ll get through this. It won’t be painless. It won’t be quick. But God will use this mess for good. In the meantime don’t be foolish or naive. But don’t despair either. With God’s help you will get through this.” The big question is asked do you trust God? If you do Mr. Lucado makes it as easy as A-B-C. “Admit your wrongdoing. Believe that Jesus is who he says he is. Commit your life to his cause.” The response page allows you to reflect a prayer & to sign off. It’s a wonderful ending to a book that carries a powerful message. I feel that message is that God will get me THROUGH my difficult times & I truly believe this because I’m a child of Jesus, the Son of God. I have certain pages highlighted which I flip to easily. If I’m in true need I read the entire book. I can’t write enough on how much this has benefited me at the cost of under $5.00. I feel if you can relate to anything I’ve written, you will greatly benefit from this book.
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Reviewed in the United States on November 20, 2023

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