SKU: 63051738003

Human CD14, His tag

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Description

Human CD14, His tagProduct Specification Species Human Synonyms Myeloid cell specific leucine rich glycoprotein Accession P08571 Amino Acid Sequence Protein sequence(P08571, Thr20 Met344, with C 10*His)

Product Specification


Species Human
Synonyms Myeloid cell-specific leucine-rich glycoprotein
Accession P08571
Amino Acid Sequence Protein sequence(P08571, Thr20-Met344, with C-10*His) TTPEPCELDDEDFRCVCNFSEPQPDWSEAFQCVSAVEVEIHAGGLNLEPFLKRVDADADPRQYADTVKALRVRRLTVGAAQVPAQLLVGALRVLAYSRLKELTLEDLKITGTMPPLPLEATGLALSSLRLRNVSWATGRSWLAELQQWLKPGLKVLSIAQAHSPAFSCEQVRAFPALTSLDLSDNPGLGERGLMAALCPHKFPAIQNLALRNTGMETPTGVCAALAAAGVQPHSLDLSHNSLRATVNPSAPRCMWSSALNSLNLSFAGLEQVPKGLPAKLRVLDLSCNRLNRAPQPDELPEVDNLTLDGNPFLVPGTALPHEGSMGGGGSHHHHHHHHHH
Expression System HEK293
Molecular Weight Theoretical:36.7kDa Actual:50-55kDa
Purity

>90% by SDS-PAGE

Endotoxin <1EU/μg
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4.
Reconstitution Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

CD14 (cluster of differentiation 14) is a human protein made mostly by macrophages as part of the innate immune system. It helps to detect bacteria in the body by binding lipopolysaccharide (LPS), a pathogen-associated molecular pattern (PAMP). CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns such as lipoteichoic acid.
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SKU: 63051738003

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4.2 ★★★★★
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Matt
Lake Worth, US
★★★★★ 5
Great weird horror
Format: Kindle
The Department of Truth: The End of the World is the first trade volume of this series, collecting issues 1-5. I don’t want to get into spoilers, but I enjoyed seeing a world building element I was familiar with in fantasy be applied to conspiracy theories. I also loved the art. It’s really stunning! I almost want to buy a print edition in addition to my Kindle/ComiXology edition because it’s so beautiful. I found the plot and concept compelling and can’t wait to read volume 2.
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Reviewed in the United States on December 19, 2022
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Maite
Charlottesville, US
★★★★★ 5
Great book
Format: Paperback
This book met all my expectations.
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Reviewed in the United States on June 30, 2023
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Will
Los Angeles, US
★★★★★ 5
Fantastic!
Format: Paperback
Very well written story along with incredible art and color. Well worth the read, can’t wait to see more.
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Reviewed in the United States on July 19, 2023
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Ziyad Baksh
Port Orchard, US
★★★★★ 4
good start.
Format: Kindle
issue 1 is dense and throws alot at you but it smooths out over time. its a solid superhero series.
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Reviewed in the United States on July 3, 2024
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Joseph
Pawtucket, US
★★★★★ 1
meh...
Format: Paperback
collecting the entire universe, so obviously i picked this up. i absolutely LOVE the stuff written by Ryan Parrott, but it seems like the some of the side stories were just thrown into the universe for the sake of 'diversity'. identity politics is injected into BOTH of the books in this series (that i have read so far... im somewhere in the middle of year two) that were written by Melissa Flores, for no reason except projection, propaganda and forced diversity quotas. the book isnt even an extreme offender or anything, but the 'community' has caused so many problems, in ever facet of society that they have attached themselves to, that i (and so many others) now see any of it as huge red flag... and that is sad, because i was raised to have the EXACT opposite viewpoint, and i did, for well over 30 years (just turned 40).
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Reviewed in the United States on April 9, 2026

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