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Description
BSP II Recombinant Rabbit mAb,PBS Only (SDT-3508-1)Product Specification Host Rabbit Antigen BSP II Synonyms Integrin binding sialoprotein; Bone sialoprotein 2; Bone sialoprotein II (BSP II); Cell binding sialoprotein; BNSP; IBSP Immunogen Synthetic Peptide Location Secreted Accession P21815 Clone Number SDT 3508 1 Antibody Type Recombinant mAb Isotype IgG Application IHC P, IF Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid
Product Specification
| Host | Rabbit |
| Antigen | BSP II |
| Synonyms | Integrin-binding sialoprotein; Bone sialoprotein 2; Bone sialoprotein II (BSP II); Cell-binding sialoprotein; BNSP; IBSP |
| Immunogen | Synthetic Peptide |
| Location | Secreted |
| Accession | P21815 |
| Clone Number | SDT-3508-1 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | Hu, Ms, Rt |
| IF | 1:2000 | Ms, Rt |
Background
BSP II (Bone Sialoprotein II) is a heavily sialylated, secreted glycoprotein that constitutes up to 10 % of bone’s non-collagenous matrix, where its clusters of acidic amino acids confer high-affinity binding to hydroxyapatite, its poly-Glu sequences nucleate mineral deposition, and its C-terminal RGD motif supports osteoblastic and odontoblastic adhesion via αvβ3 integrin, thereby acting as a key structural and signaling scaffold that synchronizes the onset of matrix mineralization with cell attachment during skeletal and cementum formation.
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Exchange/Return Notes
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