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Description
Mouse Anti-Human CD141 Antibody (S-2870)Product Specification Host Mouse Antigen CD141 Synonyms Thrombomodulin; TM; Fetomodulin; THRM; THBD Location Membrane Accession P07204 Clone Number S 2870 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Positive Sample Human Peripheral Blood cells Purification Protein G Concentration 2 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Mouse |
| Antigen | CD141 |
| Synonyms | Thrombomodulin; TM; Fetomodulin; THRM; THBD |
| Location | Membrane |
| Accession | P07204 |
| Clone Number | S-2870 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human Peripheral Blood cells |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 1:200 | Hu |
Background
CD141, also known as thrombomodulin, is a 75 kDa single-chain type I membrane glycoprotein that serves as a crucial cofactor in the protein C anticoagulant system. It is expressed on various cell types, including endothelial cells, monocytes, dendritic cells, and keratinocytes. When thrombin binds to CD141, it activates protein C, which degrades clotting factors Va and VIIIa, thereby reducing thrombin generation and preventing excessive blood coagulation. Additionally, CD141 is involved in embryonic development and atherosclerotic plaque formation. In the immune system, CD141+ dendritic cells have been shown to produce significant amounts of IFN-α in response to certain stimuli, indicating their important role in immune responses.
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4.0 ★★★★★
Based on 25 reviews
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Product Reviews
★★★★★ 5
Emotional & Powerful Read!
Format: Paperback, Format: Paperback
The Book of Cin by HM Wolfe was such an emotional and powerful read! As the first installment in The Stories Trilogy, it completely hooks you and leaves you desperate for more. I absolutely loved watching the FMC slowly grow into her abilities after years of abuse and struggling with her confidence. It felt raw and real in a way that stuck with me 🖤
This story has everything.. found family, betrayal, and moments of truly heart-wrenching grief. But what I loved the most was the belief that love and chosen family can help heal even the deepest, unseen wounds. Seeing that healing unfold made this journey incredibly rewarding ✨
If you love fantasy with emotional depth, an amazing magic system, character growth, and meaningful relationships, you NEED to pick this one up! 📚🔥
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Reviewed in the United States on March 23, 2026
★★★★★ 4
Well…
Format: Kindle
I enjoyed the book, it had an interesting plot and magic system. The book is full of smirks, hissing, and crying. OMG the crying! The FMC cries from front to back of the book! I absolutely loved Daggermouth and read this book bc that, but I feel like she had a different editor maybe?! Idk what happened, but this book would have been so much better without the MMC smirking on every page that the FMC was crying on.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
Top Book of 2024
Format: Kindle
May Contain Spoilers!
Where do I even begin?
I'm still in shock of how amazing this book was, how it touched my heart, and now how I have to wait for H. M. Wolfe to write the second. Because those last few chapters...went from 0 to 100 quick. So much new information, new relationships and loss, that now the tides have turned, and we NEED more.
This is a fantasy book of love, loss, the power of friendship, and finding one owns strength. TBOC is about Hyacinth whose home is at Asrai’s Academy for Orphans. She was torn between the safety of home or leaving it all behind for a chance at a new life. But when a mysterious messenger appears, whispering rumors of a God among Fae, everything Hyacinth thought she knew about the Realms comes crashing down, and she must now make a new journey.
This book ate me up and spit me back out. I was not anticipating the emotions I would feel within these pages. I'm talking I was laughing, then I was swooning, then I was on the edge of my seat, then I'm ready to slap someone, then I'm rooting so hard for certain characters I don't wan to stop, then my heart is broken, then I'm excited af.... it was all an emotional rollercoaster. The last few chapters contained a lot of new information, so of course as much as it doesn't leave off on a complete cliffhanger, I was over here like scraping the bottom of an ice cream cup, wanting more.
The magic system starts out ambiguous, but as you continue reading you start to get more and more to build off of and start to piece together the world H. M. Wolfe created. TBOC brings in eight main characters that test alliances, grow in friendships, fall in love, become a team, and even break bonds.
The friendship among the girls was everything. Ata is a spit fire, Pria is sweet yet terrifying. The banter and protectiveness these three had for one another made me want to join in with them for breakfast. I liked how there was multiple romances going on at once. Yes we have the main characters, but it just wasn't always about them, and it was great to see how others shifted and grew too.
And last the romance, I've never rooted so hard for two characters. We're talking slow burn between them. In the beginning you're not sure how this is all going to play out, but Landers is a tatted, "touch her and die" kind of MMC, which who cannot love that? Hyacinth definitely had to grow within the chapters and learn how to be strong, because sometimes she was making me mad and I just wanted to step in there for her. But Landers was everything she needed and it was so well written, which is why by time you get to the end you only want more of them!
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Reviewed in the United States on September 24, 2024
★★★★★ 3
cliffhanger, no 2nd book in sight
Format: Kindle
The book itself was pretty good. The plot is unique and full of suspense and action, although some of it felt redundant. I particularly enjoyed the realistic growth cycle of the female lead from abuse survivor with low self-esteem to badass warrior.
I never would have read it though if I had known this is not complete, and there is no information available on the next book.
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Reviewed in the United States on November 17, 2024
★★★★★ 4
4.5
Format: Kindle
4.5
The Book of Cin relies heavily on the progression and growth of our fmc, which I don't hate. It shows us the girl she was and what she allowed and who she then grows into by the end due to all the events that happens within the book. This journey - physically, mentally, and especially emotionally - takes us through her current and past experiences and expresses how one can grow from trauma. Her support group is invaluable, and the new relationships she forms prove to be just as prominent to her and her growth. This is truly a story that thrives on the characters growth throughout the book and sets us up in how to see her for the coming books.
My half star comes from the pacing. Though I *thoroughly* enjoyed the ending and seeing this growth take full effect, I believe that it came with just too many pages. Sitting at about 500, we get intimate and detailed scenes that we could have maybe gone without. Oftentimes, I found myself daydreaming away from the book until something more prominent peaked my interest again. I understand the depth the book goes into to fully establish this character development and the setup that this provides for the rest of the series, but I truly do believe there were scenes that could have been cut out to help with the pacing.
If you're not into slow pacing (and usually I'm not), this book is still worth the read. The ending more than makes up for it, and it is absolutely detrimental to the story that we get the events that occur and see the development take shape in front of our eyes. It makes you fist pump the sky by the end.
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Reviewed in the United States on May 20, 2025