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Description
Ki67 Mouse mAb (Cy5 Conjugate) (S-606-33)Product Specification Host Mouse Antigen Ki67 Synonyms Proliferation marker protein Ki 67, Antigen identified by monoclonal antibody Ki 67, MKI67, Ki 67 Immunogen Synthetic Peptide Location Nucleus Accession P46013 Clone Number S 606 33 Antibody Type Mouse mAb Isotype IgG1,k Application ICC, IF Reactivity Hu Purification Protein G Concentration 2 mg ml Conjugation Cy5 Physical Appearance Liquid Storage Buffer PBS, 0. 1% BSA, 0. 01% Proclin 300
Product Specification
| Host | Mouse |
| Antigen | Ki67 |
| Synonyms | Proliferation marker protein Ki-67, Antigen identified by monoclonal antibody Ki-67, MKI67, Ki-67 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | P46013 |
| Clone Number | S-606-33 |
| Antibody Type | Mouse mAb |
| Isotype | IgG1,k |
| Application | ICC, IF |
| Reactivity | Hu |
| Purification | Protein G |
| Concentration | 2 mg/ml |
| Conjugation | Cy5 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 0.1% BSA, 0.01% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| ICC | 1:100 | null |
| IF | 1:100 | null |
Background
The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation, and can be used in immunohistochemistry. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent in resting (quiescent) cells (G0). Cellular content of Ki-67 protein markedly increases during cell progression through S phase of the cell cycle. In breast cancer Ki67 identifies a high proliferative subset of patients with ER-positive breast cancer who derive greater benefit from adjuvant chemotherapy.
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4.5 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 5
The most current and inclusive medical reference available mid-2018.
Format: Hardcover, Format: Hardcover
Here’s the review I wrote for the 19th edition on 2011: I've been getting and using the Merck Manual for over 30 years to answer questions about disease for family and friends (pediatrics through geriatrics) as well as preparing to ask germane questions of physicians responsible for care of family and friends. It is comprehensive in its coverage of the etiology, diagnosis, treatment and prognosis of diseases of the human body and contains the latest research results on the treatment options. It's really not that difficult for the layman to understand the medical terminology and the result is factual understanding of the major aspects of disease which you will NOT get from the standard home health care books from Johns Hopkins, Harvard, Mayo Clinic, the AMA or even the Merck Home Health handbook. And, unlike the Merck Manual, these books directed to the laity do not contain the diagnostic information upon which physicians decide precisely what disease they are presented with. Yes, there will be much superfluous information which you may never use, but, when you want and need the information about a specific disease, here's where you should start your education.
The same holds true for the updated 2018 20th edition. I neglected to mention that this manual also contains a plethora of ancillary information including thorough sections on pediatrics, geriatrics, injuries, bites and stings, patient care, alternative medicine, dietary supplements, rehabilitation, normal test values and even legal issues such as advance directives. Yup, it’s pricey, but it’s always proved to be valuable to me.
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Reviewed in the United States on June 15, 2018
★★★★★ 5
Great reference book
Format: Hardcover
If you only have one medical resource book in your house, I recommend this one. Very thorough book.
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Reviewed in the United States on March 3, 2026
★★★★★ 5
Good to Have
Format: Hardcover
This is a comprehensive manual. I bought it because of the difference of opinions of different doctors and vets that we received when our cat was sick. We spent over $6,000+ and found out he only had 1 of the 7 symptoms of his diagnosis and the hospital could not find the reason for his weight loss. Many years ago a human Merck Manual helped us discover that the specialist was using one. After coming out of the hospital and during a followup visit, I asked what is the next step to take. I advised him we bought a Merck Manual and can read it just as well as him and was not happy. He sent us to an Electrophysiologist, a speciality we never knew existed.
Kitty gained weight again, just needed to peak his appetite with Instinct Rabbit and Duck dry cat food. Apparently, his smell was off and Instinct coats their kibble with the flavor you are buying. It wasn’t easy finding the right one because he is food specific and it must be kibble. We donated all the ones recommended and others we thought he would the rescues. When we first adopted him as a kitten, he was sneezing mucous tinted with blood and vet said he would grow out of it. He did but ….
Highly recommend double checking and / or getting a 2nd opinion, human or otherwise.
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Reviewed in the United States on January 26, 2024
★★★★★ 5
Compact detailed reference work
Format: Hardcover
This is the next in a series of, th most recent version. Contains a volume of medical information of many medical topics.a great reference product.
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Reviewed in the United States on November 21, 2025
★★★★★ 4
It is great to use if you are trying to understand the ...
Format: Hardcover
I am entering my second year of PA school and I use this book 2-3 times a week.
Summary: This is clearly a book for practitioners ONLY (or soon to be). If you are a medical, PA, or NP student, consider delaying buying this book until your 2nd or 3rd year. This book can feel very overwhelming, especially since most of the time you have a quick question and it may take several minutes to find it. It is great to use if you are trying to understand the entire picture of a disease, especially in a clinical context. It starts by giving you 1-2 paragraphs of pathophysiology, then gives you the process of diagnosing, the clinical presentation, the ddx, labs, tx, prognosis, and "pearls" of the disease. I like using this when I am learning about a specific disease for the first time. Please understand, there is no one book that can answer every question of medicine. This however, is as close as you will get with the exception of a few things here and there. Overall, great book to supplement my classroom lectures.
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Reviewed in the United States on July 5, 2018