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Description
NuMA Recombinant Rabbit mAb,PBS Only (SDT-474-241)Product Specification Host Rabbit Antigen NuMA Synonyms Nuclear mitotic apparatus protein 1; Nuclear matrix protein 22 (NMP 22); Nuclear mitotic apparatus protein (NuMA protein); SP H antigen; NUMA1; NMP22 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Cell membrane Accession Q14980 Clone Number SDT 474 241 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF, ICFCM Reactivity Hu, Ms, Rt Purification Protein A
Product Specification
| Host | Rabbit |
| Antigen | NuMA |
| Synonyms | Nuclear mitotic apparatus protein 1; Nuclear matrix protein-22 (NMP-22); Nuclear mitotic apparatus protein (NuMA protein); SP-H antigen; NUMA1; NMP22 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Cell membrane |
| Accession | Q14980 |
| Clone Number | SDT-474-241 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF, ICFCM |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:100 | |
| ICC | 1:500 | |
| IF | 1:500 | |
| ICFCM | 1:500 |
Background
NMP22 is a protein located in mitotic spindle of nucleus of the cell. It allows cell replications after microtubule assembly and fragmentation of genome. NMP22 is released from apoptotic cells and its concentration rises in urine of bladder cancer patients. It is considered to be most reliable, noninvasive, highly sensitive but poorly specific marker of malignancy in voided urine.
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