Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 28 - Sep 2
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Mouse Anti-Mouse NK1.1 Antibody (S-R480)Product Specification Host Mouse Antigen NK1. 1 Synonyms Killer cell lectin like receptor subfamily B member 1B allele A; CD161 antigen like family member B; Lymphocyte antigen 55b (Ly 55b); NKR P1 34; Natural killer cell surface protein NKR P1B allele SJL BALB (NKR P1B); CD161b; Ly55b; Nkrp1b; Klrb1b Location Membrane Accession P27812 Clone Number S R480 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample C57BL 6
Product Specification
| Host | Mouse |
| Antigen | NK1.1 |
| Synonyms | Killer cell lectin-like receptor subfamily B member 1B allele A; CD161 antigen-like family member B; Lymphocyte antigen 55b (Ly-55b); NKR-P1 34; Natural killer cell surface protein NKR-P1B allele SJL/BALB (NKR-P1B); CD161b; Ly55b; Nkrp1b; Klrb1b |
| Location | Membrane |
| Accession | P27812 |
| Clone Number | S-R480 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
NK1.1, also known as KLRB1C and NKRP1C, is a type II integral membrane glycoprotein with a C-type lectin domain and belongs to the NKR-P1 family of cell surface receptors. It is expressed as a disulfide-linked homodimer on all NK and NKT cells in some strains of mice, particularly serving as a good marker for these cell types in the C57BL/6 genetic background. NK1.1 associates with the ITAM-bearing γ-chain adaptor molecule and does not engage ligands with an MHC class-I-like fold, but interacts with C-type lectin-like CLEC2 glycoproteins. Although crosslinking of the NK1.1 receptor using a specific mAb can induce NK cell-mediated cytotoxicity and effector cytokine secretion, the in vivo functions of NK1.1 and the identity of its ligand(s) are still not fully understood.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy