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Description
FGL2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms FGL2, T49, pT49 Accession P12804 Amino Acid Sequence Pro197 Pro432, with C terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH Expression System HEK293 Molecular Weight 38 43kDa Purity >95% by SDS
Product Specification
| Species | Mouse |
| Synonyms | FGL2, T49, pT49 |
| Accession | P12804 |
| Amino Acid Sequence | Pro197-Pro432, with C-terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 38-43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Feng Y. et al. (2020) Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer. Med Sci Monit. 26: e923531. 2、Hou X X. et al. (2021) Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. Commun Biol. 4(1): 499. |
Background
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. Fibrinogen-like protein 2 (FGL2) exists in both soluble and membrane forms. Soluble fibrinogen-like protein 2 (sFGL2) has been recently identified as a novel effector molecule of Tregs and plays a pivotal role in regulating both innate and adaptive immunity. FGL2 mediates its immunosuppressive activity by binding to inhibitory FcγRIIB (CD32B) receptors expressed by antigen presenting cells (APC), including dendritic cells (DC) and B cells, and thus sFGL2 may inhibit the maturation of DC, resulting in the suppression of effector T cell responses and inducing apoptosis of B cells. However, nothing is known about sFGL2 and its potential roles in endometriosis.
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4.8 ★★★★★
Based on 7 reviews
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Product Reviews
★★★★★ 5
Easy to use
Style: 6-Speaker
This was a lifesaver. After buying a house, I discovered a huge mess of audio cables wired throughout the place, and this plate made it possible to finally get everything organized.
Quality is decent, not the best, but good for the value.
Super easy to use and connect even old wires to it from the back.
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Reviewed in the United States on December 31, 2025
★★★★★ 5
These wall plates look good and work well
Style: 2-Speaker
I used these wall plates for my home theater system. They are easy to install, look good, and accepted my banana plugs perfectly. They make my installation look tidy and I am pleased with the outcome. I have used other Cable Matters products in past and have always been happy with the results.
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Reviewed in the United States on January 12, 2026
★★★★★ 5
Excellent, clean look
Style: 1-Speaker
Great wall plate for that clean, in wall wiring look. Easy to install and connections are solid.
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Reviewed in the United States on November 26, 2025
★★★★★ 4
Great...but could be a bit better
Style: 2-Speaker
Almost perfect. Easy to screw apart and insert wires to both the back and to the front, or do what I did and screw the wire onto the back and then use a banana plug for the front. My only complaints are that the back piece sits off the wall a little, so the plate doesn't fit flat and tight against the wall. It leave a little gap around the edges. The other complaint is that the back piece has some flex in it, which makes me nervous when I push plugs into and out of it. I think it probably will hold up fine, but it feels a little oogy to push banana plugs into it and see it flex. Comes with all the hardware needed. Just need a philips screwdriver and wire cutters and you're good to go. Super easy to use, and way better than the spring loaded connections it replaced.
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Reviewed in the United States on July 12, 2017
★★★★★ 5
Built well
Style: 4-Speaker
Still working great no issues with sound quality.
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Reviewed in the United States on April 17, 2026
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