SKU: 67604960522

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)

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Description

Alexa Fluor® 700 Mouse Anti-Human CD45RO Antibody (S-R401)Product Specification Host Mouse Antigen CD45RO Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); T200; CD45; PTPRC Location Cell membrane, Synapse Accession P08575 Clone Number S R401 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Hu Purification Protein A Concentration 0. 2 mg ml Conjugation Alexa Fluor 700 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability &

Product Specification


Host Mouse
Antigen CD45RO
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); T200; CD45; PTPRC
Location Cell membrane, Synapse
Accession P08575
Clone Number S-R401
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 700
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD45RO is a transmembrane protein tyrosine phosphatase with a molecular weight of approximately 180-220 kDa, belonging to a splice variant of the leukocyte common antigen CD45 family. It is generated through alternative splicing of the CD45 gene, lacking the exon-encoded A, B, and C regions, thus possessing the smallest extracellular domain among CD45 isoforms. CD45RO is predominantly expressed on memory T cells (including effector memory T cells and central memory T cells), activated T cells, monocytes, and macrophages, serving as a key surface marker for memory T cells. Its intracellular domain contains two highly conserved protein tyrosine phosphatase domains, which regulate the phosphorylation status of Src family kinases (e.g., Lck and Fyn) and play a crucial role in T-cell receptor (TCR) signaling, modulating T-cell activation, proliferation, and immune responses. CD45RO expression is closely associated with pathological processes such as chronic inflammation, autoimmune diseases, and transplant rejection, and it is also an important indicator for assessing T-cell immune function in HIV infection. Given its dynamic expression levels reflecting immune status, CD45RO holds potential value in immune monitoring and disease diagnosis.

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SKU: 67604960522

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IdoArt
Whiting, US
★★★★★ 5
Sturdy, doesn't leak
I love these! Lots of space for family-style dinners or potlucks. Sturdy and leak-proof.
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Reviewed in the United States on May 18, 2026
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Linda Vandenburg
Alexandria, US
★★★★★ 4
these are very nice platter/plates
these are not quite as thick as I was hoping for, but they’re really nice. I guess I’m just used to using paper plate holders underneath them but if you use two together, they’ll hold just about anything that you can put on them.
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Reviewed in the United States on May 20, 2026
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Ms Cox
Chelsea, US
★★★★★ 5
Strong and durable
My everyday plates..cheap enough and strong enough ..buy all the time for microwaving and leftovers..they are strong enough to keep for a second round at the table
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Reviewed in the United States on May 15, 2026
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Lisa S.
Birmingham, US
★★★★★ 5
Sturdy and eco friendly
Color: Natural
Great plates and very sturdy!!!!
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Reviewed in the United States on May 26, 2026
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Cara Clark
San Leandro, US
★★★★★ 5
Ideal for bigger holiday meals
Color: White
Sturdy & great size for Easter, Thanksgiving, Christmas & potlucks or bigger meals
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Reviewed in the United States on May 15, 2026

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