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Description
S-RMab® IDO1/Indoleamine 2,3-dioxygenase Recombinant Rabbit mAb (S-259-62)Product Specification Host Rabbit Antigen IDO1 Indoleamine 2,3 dioxygenase Synonyms Indoleamine pyrrole 2,3 dioxygenase, IDO, INDO Immunogen Recombinant Protein Location Cytoplasm Accession P14902 Clone Number S 259 62 Antibody Type Recombinant mAb Application WB, ICC, ICFCM, IHC Reactivity Hu Purification Protein A Concentration 0. 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin
Product Specification
| Host | Rabbit |
| Antigen | IDO1/Indoleamine 2,3-dioxygenase |
| Synonyms | Indoleamine-pyrrole 2,3-dioxygenase, IDO, INDO |
| Immunogen | Recombinant Protein |
| Location | Cytoplasm |
| Accession | P14902 |
| Clone Number | S-259-62 |
| Antibody Type | Recombinant mAb |
| Application | WB, ICC, ICFCM, IHC |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IHC | 1:200-1:1000 | null |
| ICC | 1:100 | null |
| ICFCM | 1:100 | null |
Background
Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO) is a heme-containing enzyme physiologically expressed in a number of tissues and cells, such as the small intestine, lungs, female genital tract or placenta. IDO is an important part of the immune system and plays a part in natural defense against various pathogens. It is produced by the cells in response to inflammation and has an immunosuppressive function because of its ability to limit T-cell function and engage mechanisms of immune tolerance. Emerging evidence suggests that IDO becomes activated during tumor development, helping malignant cells escape eradication by the immune system. Expression of IDO has been described in a number of types of cancer, such as acute myeloid leukemia, ovarian cancer or colorectal cancer.
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4.6 ★★★★★
Based on 30 reviews
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Product Reviews
★★★★★ 5
Indestructible Toys My Dobermans ❤️
Size: Large, Color: Mesh Green
Actually Respect! goDog Is a Lifesaver
The variety of size and colors are phenomenal 😇
I have two Dobermans — serious, determined power chewers — and I’ve spent years trying to find toys that survive even a few days.
I’ve tried the big brands (Kong, Goughnuts, Jolly Ball, you name it) — and while some toys last a little while, almost everything eventually ends up shredded, de-squeaked, or in pieces.
goDog toys are the ONLY plush toys my Dobermans won’t destroy.
We own multiple goDog toys now — dragons, dinosaurs, lizards — mostly in the large size (perfect for Dobermans), but even a few medium-sized ones hold up surprisingly well.
Here’s what’s amazing:
• They love them — actually carry them around, toss them, chew them gently, and squeak them happily.
• They do not rip them apart — no matter how much tugging, chewing, or wrestling happens.
• Large sizes are best for Dobermans (and other big breeds) — but even mediums survive for calmer play sessions.
• No ripped seams, no stuffing everywhere, and no destroyed squeakers after months of use.
What makes goDog toys different?
The secret is their Chew Guard Technology —
• A reinforced, high-strength inner mesh layer under the soft plush
• Double-stitched seams
• Durable yet flexible material that somehow resists punctures, tears, and brutal shaking
The outside stays soft and fun, but the inside is built like armor.
It’s NOT a super hard rubber or rough canvas — it still feels like a cuddle toy, but it’s engineered to survive serious chewing.
Materials include:
• Durable polyester plush
• Chew Guard inner lining (high-tensile mesh fabric)
• Reinforced stitching
• Non-toxic squeakers
• Safe for dogs to play with long-term
Real Owner Advice:
• Always size up if you have a heavy chewer — large sizes are a must for Dobermans or similarly strong breeds.
• Medium sizes are fine if you supervise or your dog is more moderate with toys, but the large toys are built tougher overall.
Final Thoughts:
If you have big dogs, strong jaws, or just tired of wasting money on destroyed toys — goDog toys are a must.
No other plush-style toy even comes close.
My Dobermans will destroy almost anything… but they treat their goDog toys like treasured companions. No holes, no rips, just happy dogs.
Follow me here on Amazon for more honest, dog-tested reviews! Like this review if it helped — I’ll be uploading even more proven tough toys and pet essentials soon!
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Reviewed in the United States on April 29, 2025
★★★★★ 4
Surface Fabric is very durable
Size: Small, Color: Hot Pink
Surface Fabric is very durable, but the squeaker didn't last two months. I have urged the manufacturer to find a strong more durable squeaker for their product. My dogs really enoys it when the speaker works. One of his 3 work. I have just bought two more he likes them so much. He takes it to bed every night to catch it once or twice before sleeping. Also loves to catch it a few times during the day.
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Reviewed in the United States on April 11, 2026
★★★★★ 5
Best. Toy. Ever. For My Superchewer!
Size: Large, Color: Skinny Green, Size: Large, Color: Skinny Green
Best toy ever! My dog destroys toys. Usually within about 15 minutes, she has de-squeakered and defluffed them. By the second day, she has tug-of-war-ed them to shreds.
From the time we got this adorable dragon out of the package, she LOVED it. She set to work. It’s been a week, and while she has dewinged him, he lost his squeaker after a few days, and he looks a bit rough, he’s still in one piece! And, we’ve had HOURS of tug-of-war with minimal rips! She’s obsessed 😍 I ordered two more today. We’ve finally found the perfect toy for my baby!
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Reviewed in the United States on January 18, 2026
★★★★★ 5
My 90 lb. Pitbull's All-Time Fave Toy
Size: Large, Color: Coral, Size: Large, Color: Coral
I ordered a plethora of new toys for Bruce to keep him occupied while I am working remotely from home. Poor guy gets so bored while I'm stuck in front of my computer 8+ hours a day. All the other toys are animated, but this one is just a big floppy chewy squeaky toy. Bruce quickly lost interest in all the other chirping, hopping, and twirling toys and fell in love with "Diny". When I opened Diny and gave it to Bruce, he had the elated and surprised look of a 3 yr old at Christmas. And he stayed that happy for hours, and then each time he picked up Diny to play. Diny became his go-to toy over all others (and there are many!). It is well made out of durable fabric, and they did not stuff it full of kapoc (I hate kapoc in dogs toys!). And it is delightfully low-tech. Normally he tears a squeaky toy apart as soon as he can isolate the squeaky mechanism. But cleverly, the squeaky box is loose in the long belly so it moves from one end to the other as the toy is handled. That made it difficult for Bruce to locate it. The toy remained in good condition for 2 weeks of near constant attention by Bruce. But yesterday he zeroed in on the squeaky box and ripped Diny to shreds. I was sad to see Diny go so soon. But boy-howdy was Bruce happy with it. I'm gonna buy another because we liked it so much. And so did I : )
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Reviewed in the United States on May 23, 2024
★★★★★ 5
This is one “under the radar” gem!!
Size: Large, Color: Coral
This is one “under the radar” gem!! Very strong internal squeaker and way tougher than it looks. My big 125lb Shepard-Husky mix gave it heck, then made it his new buddy. He’ll occasionally give it the business but on the whole, it’s surprisingly tough and my big boy loves it. Nice price!!
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Reviewed in the United States on May 10, 2026