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Description
Anti-CD124 Monoclonal Antibody(Dupilumab)Product Specification Host Human Synonyms Interleukin 4 receptor subunit alpha, IL 4 receptor subunit alpha, IL 4R subunit alpha, IL 4R alpha, IL 4RA, CD124 Accession P24394 Clone Number S SC022 Antibody Type Recombinant mAb Isotype IgG4,k Application Blocking of IL 4R signaling Functional assays Purification Protein A Concentration 2 mg ml Endotoxin <1EU mg Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, containing no
Product Specification
| Host | Human |
| Synonyms | Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124 |
| Accession | P24394 |
| Clone Number | S-SC022 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG4,k |
| Application | Blocking of IL-4Rα signaling Functional assays |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| ELISA | 1.221-5000 ng/ml |
Background
Dupilumab is a monoclonal antibody blocking interleukin 4 and interleukin 13, used for allergic diseases such as eczema (atopic dermatitis), asthma and nasal polyps which result in chronic sinusitis. It is also used for the treatment of eosinophilic esophagitis and prurigo nodularis.
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