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Description
AQR/IBP160 Recombinant Rabbit mAb (S-1329-248)Product Specification Host Rabbit Antigen AQR IBP160 Synonyms RNA helicase aquarius; Intron binding protein of 160 kDa (IBP160); KIAA0560 Immunogen Synthetic Peptide Location Nucleus Accession O60306 Clone Number S 1329 248 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu Positive Sample HeLa, HEK 293, HepG2 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer
Product Specification
| Host | Rabbit |
| Antigen | AQR/IBP160 |
| Synonyms | RNA helicase aquarius; Intron-binding protein of 160 kDa (IBP160); KIAA0560 |
| Immunogen | Synthetic Peptide |
| Location | Nucleus |
| Accession | O60306 |
| Clone Number | S-1329-248 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, ICC |
| Reactivity | Hu |
| Positive Sample | HeLa, HEK-293, HepG2 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu |
| ICC | 1:500 | Hu |
Background
AQR/IBP160 protein, also known as Aquarius homolog or Intron-binding protein of 160 kDa, is a spliceosomal intron-binding protein involved in pre-mRNA splicing and small nucleolar ribonucleoprotein (snoRNP) biogenesis. It links the position-dependent assembly of intron-encoded box C/D snoRNPs to pre-mRNA splicing, playing a key role in the folding of snoRNA sequences. This protein has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang. It binds to introns of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns during the late stages of splicing.
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