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Description
CD112/Nectin-2 Recombinant Rabbit mAb (S-2404-66)Product Specification Host Rabbit Antigen CD112 Nectin 2 Synonyms Nectin 2; Herpes virus entry mediator B (Herpesvirus entry mediator B; HveB); Nectin cell adhesion molecule 2; Poliovirus receptor related protein 2; HVEB; PRR2; PVRL2; NECTIN2 Immunogen Synthetic Peptide Location Cell membrane Accession Q92692 Clone Number S 2404 66 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample HeLa, SH SY5Y, 293T, NIH
Product Specification
| Host | Rabbit |
| Antigen | CD112/Nectin-2 |
| Synonyms | Nectin-2; Herpes virus entry mediator B (Herpesvirus entry mediator B; HveB); Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2; HVEB; PRR2; PVRL2; NECTIN2 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | Q92692 |
| Clone Number | S-2404-66 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | HeLa, SH-SY5Y, 293T, NIH/3T3, Neruo-2a |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu, Ms, Rt |
| IHC-P | 1:250 | Hu |
Background
CD112, also known as PRR2 or Nectin-2, is a 58 kDa protein expressed in myeloid cells. It is a component of adherens junctions and plays a role in cell adhesion. CD112 is a member of the nectin family, which are calcium-independent immunoglobulin superfamily proteins that mediate cell-cell adhesion through homophilic and heterophilic interactions. Nectins are involved in the formation and maintenance of adherens junctions and tight junctions, and they regulate various cellular behaviors such as cell adhesion, growth, differentiation, migration, and apoptosis.
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