SKU: 70012854429

Alexa Fluor® 647 Rat Anti-Mouse PD-1 (CD279) Antibody (S-R496)

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Description

Alexa Fluor® 647 Rat Anti-Mouse PD-1 (CD279) Antibody (S-R496)Product Specification Host Rat Antigen PD 1 (CD279) Synonyms Programmed cell death protein 1; Protein PD 1; mPD 1; Pdcd1 Location Cell membrane Accession Q02242 Clone Number S R496 Antibody Type Rat mAb Isotype IgG2a Application FCM Reactivity Ms Purification Protein G Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25% Glycerol, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2

Product Specification


Host Rat
Antigen PD-1 (CD279)
Synonyms Programmed cell death protein 1; Protein PD-1; mPD-1; Pdcd1
Location Cell membrane
Accession Q02242
Clone Number S-R496
Antibody Type Rat mAb
Isotype IgG2a
Application FCM
Reactivity Ms
Purification Protein G
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300

Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5 μl per million cells in 100μl volume

Background

Programmed cell death protein 1 (PD-1), also known as CD279, is a type I transmembrane protein and a member of the CD28 immunoglobulin superfamily, encoded by the _PDCD1_ gene. It is primarily expressed on the surface of various immune cells, including T cells, B cells, macrophages, dendritic cells, and natural killer cells. PD-1 plays a crucial role in regulating immune responses by binding to its ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC), which are expressed on antigen-presenting cells and tumor cells. When PD-1 interacts with its ligands, it triggers inhibitory signals that downregulate T cell activity, preventing excessive immune responses and promoting self-tolerance. However, this pathway can also be exploited by cancer cells to evade immune surveillance, leading to tumor progression. As a result, PD-1 has become a key target in cancer immunotherapy, with several anti-PD-1 antibodies approved for treating various cancers, achieving significant and durable efficacy in some patients.

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SKU: 70012854429

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4.5 ★★★★★
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K
Verified Purchase
Kindle Customer
Chelsea, US
★★★★★ 4
So good and great price!
Flavor Name: Prickly Pear, Size: 25.4 Fl Oz (Pack of 1)
It taste good and what a great price! However it tastes very different than the Monin brand that I love. To me it taste a lot like the DaVinci cherry which btw is so YUMMY. Its not bad just different.
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Reviewed in the United States on April 17, 2026
G
Verified Purchase
GIRLY
Birmingham, US
★★★★★ 5
Best ever
Flavor Name: Banana Bread, Size: 25.4 Fl Oz (Pack of 1)
I’ve tried a few others brands. This one is the best. I’ve drank flavored coffee for years. Banana bread is 10 star worthy, rich in flavor and it doesn’t take a lot. Very smooth. I like it alot. I’m not looking for another brand because I already know where it’s good. I don’t mess around with my coffee ☕️ 🍌 🌰 🍞
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Reviewed in the United States on May 16, 2026
D
Verified Purchase
DávÏd Árí ÁmÏr
Chelsea, US
★★★★★ 5
Try it in a carrot cake, it is yummy!!!
Flavor Name: Chai Tea Concentrate, Size: 25.4 Fl Oz (Pack of 1)
I have without question been extremely happy with all of the DaVinci syrups, and products I have purchased. This chai syrup really was perfect for making chai lattes for my wife, and adding some chai flavor to other drinks, and I even used it in some cheesecake frosting, and inside of a carrot cake recipe, and it was perfect. I strongly suggest that you try it in carrot cake, and in other things like frosting. The chai carrot cake I made ended up being the perfect compliment to a nice cappuccino. I made a bunch of cupcakes using the carrot cake mix with the chai,and the chai cream cheese frosting, and with a nice coffee made the coffee taste better, and the carrot cake complimented the coffee perfectly. I have made them a few times now, and will say don't overdo and put too much frosting onto the carrot cake, and it is something I can't recommend enough. I actually have been using it more it making baked goods, and little desserts more then for chai lattes even. It just really works perfectly in them.
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Reviewed in the United States on April 8, 2026
S
Verified Purchase
Shannon
Bozeman, US
★★★★★ 5
Great deal! Yummy!
Flavor Name: Blue Raspberry, Size: 25.4 Fl Oz (Pack of 1)
Using for our dirty soda bar, this brand is a delicious addition to our flavors! Nice bottle, great price!
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Reviewed in the United States on May 27, 2026
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Verified Purchase
Nicholas
Grantham, US
★★★★★ 4
Comparing to the coffee giant version
Flavor Name: Brown Sugar, Size: 25.4 Fl Oz (Pack of 1), Flavor Name: Brown Sugar, Size: 25.4 Fl Oz (Pack of 1)
Starbucks comparison (from a personal standpoint): I’m fortunate enough to have a bottle of Starbucks Brown Sugar. Problem is, I’m almost out. Looking around at some alternative options, and reading the reviews- I see some saying this is a good substitute. Because I happen to have the syrup on hand, I figured I should see if it is, because it would be great given the low cost of DaVinci syrup. This picture I’m attaching is just to see the color difference. Consistency wise, the DaVinci syrup is much lighter, more runny. The Starbucks is definitely a thicker liquid, that runs much slower. Flavor is the big one: DaVinci is lighter on taste, and sweeter. The best way to describe the flavor is comparing DaVinci’s to 100% real maple syrup that’s been diluted down with water. It’s good, but not really similar (in my opinion) to Starbucks Brown Sugar. Starbucks is more smokey in flavor, more strong/bold. My drinks are made using espresso, oak milk, cinnamon powder, and ice. I made my drink the same way, but used DaVinci Syrup this time. I found that the same amount of syrup that I use for the Starbucks, didn’t feel like it had a strong enough flavor. What did I do? I added an extra ounce of DaVinci hoping to get a stronger flavor. The problem is, DaVinci is more sweet than the Starbucks syrup (in my opinion) and ended up making my drink taste too sweet. It’s sweet enough that I’m not going to finish drinking it. I’m not knocking the DaVinci syrup itself. I think it’s a good brand and a good flavor. It’s just not the flavor I was hoping would solve my issue for a Starbucks imitation. I would encourage anyone to still try this syrup, but do so to enjoy it for being its own flavor.
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Reviewed in the United States on January 18, 2026

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