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Description
IgG4 Fc His tag Protein, HumanProduct Specification Species Human Synonyms Ig gamma 4 chain C region, IGHG4 Accession P01861 Amino Acid Sequence Glu99 Gly326, with C 10*His Expression System HEK293 Molecular Weight Theoretical: 27. 3kDa Actual: 33kDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer 0. 2M PBS, pH7. 4. Reconstitution Reconstitute no more than 1 mg mL according to the size in deionized
Product Specification
| Species | Human |
| Synonyms | Ig gamma-4 chain C region, IGHG4 |
| Accession | P01861 |
| Amino Acid Sequence | Glu99-Gly326, with C-10*His |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.3kDa Actual:33kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | 0.2M PBS, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Fc binds to various cell receptors and complement proteins. In this way, it mediates different physiological effects of antibodies (detection of opsonized particles; cell lysis; degranulation of mast cells, basophils, and eosinophils; and other processes).
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