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Description
AKAP4 Recombinant Rabbit mAb,PBS Only (SDT-4196)Product Specification Host Rabbit Antigen AKAP4 Synonyms A kinase anchor protein 4; AKAP 4; A kinase anchor protein 82 kDa (AKAP 82; hAKAP82); Major sperm fibrous sheath protein (HI); Protein kinase A anchoring protein 4 (PRKA4); AKAP82 Location Cell projection Accession Q5JQC9 Clone Number SDT 4196 Antibody Type Recombinant mAb Isotype IgG Application IHC P, IF Reactivity Hu Purification Protein A Concentration 1 mg ml Conjugation Unconjugated
Product Specification
| Host | Rabbit |
| Antigen | AKAP4 |
| Synonyms | A-kinase anchor protein 4; AKAP-4; A-kinase anchor protein 82 kDa (AKAP 82; hAKAP82); Major sperm fibrous sheath protein (HI); Protein kinase A-anchoring protein 4 (PRKA4); AKAP82 |
| Location | Cell projection |
| Accession | Q5JQC9 |
| Clone Number | SDT-4196 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | Hu |
| IF | 1:500 | Hu |
Background
AKAP4, the most abundant protein of the sperm fibrous sheath, is a testis-enriched scaffolding protein that simultaneously binds PKA via dual-specificity anchoring sites and PKC through polybasic motifs, thereby acting as a cAMP/PKA ↔ PKC/ERK1/2 switch that is phosphorylated on Ser/Tyr during capacitation to direct the kinase cascade to the flagellar principal piece, mid-piece and post-acrosomal region, enabling progressive motility and male fertility while also moonlighting in multiple cancers where its cytoplasmic/membrane accumulation drives proliferation, EMT and metastasis through the Shh and Wnt/β-catenin pathways.
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4.1 ★★★★★
Based on 26 reviews
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Product Reviews
★★★★★ 5
Works, and no residue!
Style: SPF 50 (Pack of 2), Size: 5.5 Ounce (Pack of 2)
I love that I can just use my FSA account to buy this.
The sunscreen works well and does not irritate my kids sensitive skin. What I like the most is that it does not leave residue everywhere so I can do a quick spray on the kids every morning before daycare. I also spray my son's head because he has a very fair skin and does not wear a hat at daycare.
It seems to be doing well by the pool too.
Good value pack.
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Reviewed in the United States on June 27, 2025
★★★★★ 5
Must have sunscreen for kids!
Style: SPF 50 (Pack of 3), Size: 5.5 Fl Oz (Pack of 3)
This is our favorite sunscreen. It is easy to apply stays on and my kids do not get burned. I have a 9, 8 and 6 year-old we live in Florida and this is the only sunscreen we buy for their body. It does not cause any skin irritation.
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Reviewed in the United States on February 19, 2026
★★★★★ 5
Light white cast, blends well
Size: 4 Ounce (Pack of 1)
I was recently influenced that I should be using mineral sunscreens to protect the environment as well as my skin from UV rays, so I've been on a search for the perfect mineral sunscreen. I saw online that it's difficult to find a sunscreen without white cast in the states, but I think this Alba lotion is as close as I've gotten. The body and face lotion is a little thicker than the lotion marketed as just for the face. The body lotion blends out easily, but there is a light white cast. I used baby oil mixed with my bronzer over the top after it had set in, and it's indistinguishable from a natural skin tone now (and a shimmer bronzer just looks good in the sun). One thing is that the picture in the listing says spf 50, but the one I received is spf 45. (but I was seriously using spf 15 with mica shimmer added for the last 20 years of my life, so I think I'm going to be fine with spf 45)
I tried the cetaphil mineral face and body lotion, and it left a white cast. I tried the aveeno mineral face and body sunscreen and it was even more white and chalky. It made me feel scaly. I even tried the Oars and Alps mineral face and body lotion with jojoba oil, and that one left me with a white cast worse than all of them.
For reference, I am pale, and I use self tan lotion, but these other mineral sunscreens made me look chalky. I also had my partner use all of these products, hopeful that they might work differently on other skintypes. I'm fair and acne prone, and my partner is darker in complexion with dry skin. I looked well blended compared to how ghostly he was. I was especially surprised because Oars and Alps was marketed toward outdoorsy men, and marketed as moisturizing with the jojoba oil. He and I both found the Oars + Alps products to be greasy, sticky, white, and transferable to clothes and anything else you touch. This alba lotion is in too small of packaging, and takes longer to apply than spray sunscreens, but it feels the best, looks the best, and especially I'm impressed with the face lotion.
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Reviewed in the United States on July 21, 2023
★★★★★ 5
works great
Size: 4 Ounce (Pack of 1)
very nice!!! This is my fav sunscreen. I wear in on my face and on the back of my hands. its a workout to rub it in the skin. so what I have found is if i just dott my face with this and after 15 minutes or so I spread it on to the skin...spreads easily. does not have a strong smell, its almost odorless, does make the face look a little whiteish.
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Reviewed in the United States on November 30, 2025
★★★★★ 4
Highly effective. Application requires patience.
Size: 4 Ounce (Pack of 1)
Things that I loved about this sunscreen lotion:
Excellent barrier against the sun rays
No nasty chemicals in the ingredients list
Ability to purchase a smaller bottle
Price is competitive with similar items
My child had NO reaction to this product while in the sun and water
Things that I didn't care for:
How thick it is (although it could be part of why it is excellent protection)
How long it takes to apply, multiple times to rub in
How chalky white it is on the skin before absorption
My daughter has eczema. In her toddler and younger years, it was in the joints of the arms and legs. She is now 9 and began having breakouts on her face after we spent a day in the sun or at the beach. Pink, flaky areas would hurt, even on her eyelids. We took her to a couple of doctors and they suggested changing her sunscreen to one that is only mineral based. I was beginning to think she was allergic to the sun or sand. We have used this a couple of times now at the pool and beach and she has not had another episode.
Although this goes on thick and you have to rub it in for a few minutes, I will continue using it on her face. I did purchase a different brand of mineral sunscreen for easier application on her body, but she wasn't having a severe reaction elsewhere. If your child has any eczema issues that are exacerbated with the sun, salt or chlorine, I would highly recommend this product for at least the face. It's worth it.
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Reviewed in the United States on June 1, 2023