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Description
Aquaporin 1/AQP1 Recombinant Rabbit mAb (S-794-79)Product Specification Host Rabbit Synonyms Aquaporin 1, Aquaporin CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, CHIP28 Immunogen Synthetic Peptide Location Cell membrane Accession P29972 Clone Number S 794 79 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP, IF Reactivity Hu, Ms, Rt Predicted Reactivity Sh, Bv, Or Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Synonyms | Aquaporin-1, Aquaporin-CHIP, Urine water channel, Water channel protein for red blood cells and kidney proximal tubule, CHIP28 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P29972 |
| Clone Number | S-794-79 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP, IF |
| Reactivity | Hu, Ms, Rt |
| Predicted Reactivity | Sh, Bv, Or |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 | |
| IF | 1:2000 | |
| IP | 1:50 |
Background
AQP-1 is a widely expressed water channel, whose physiological function has been most thoroughly characterized in the kidney. It is found in the basolateral and apical plasma membranes of the proximal tubules, the descending limb of the loop of Henle, and in the descending portion of the vasa recta. Additionally, it is found in red blood cells, vascular endothelium, the gastrointestinal tract, sweat glands, lungs, and the central nervous system. It is a homotetramer with six bilayer spanning domains and N-glycosylation sites, and functions as both a molecular water channel protein and as a non-selective cation channel gated by cyclic guanosine monophosphate (cGMP).
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