Pay in installments of $53.75 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Sep 4 - Sep 9
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Biotinylated TSLP His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms thymic stromal lymphopoietin Accession Q969D9 1 Amino Acid Sequence Tyr29 Gln159 with His&Avi Tag at the C Terminus Expression System HEK293 Molecular Weight 20 33kDa (Reducing) Purity 95% by SDS PAGE & > 95% SEC HPLC Conjugation Biotin Tag Avi Tag, His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, PH7. 4, 5% trehalose Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in
Product Specification
| Species | Human |
| Synonyms | thymic stromal lymphopoietin |
| Accession | Q969D9-1 |
| Amino Acid Sequence | Tyr29-Gln159 with His&Avi Tag at the C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 20-33kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE & > 95% SEC-HPLC |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, PH7.4, 5% trehalose |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. |
| Reference | 1.Lee YS, Noh DI, Lee SJ, Jeon MH, Kim YR, Jang WJ, Lee EW. Anti-inflammatory and barrier-restoring effects of heat-killed Lactiplantibacillus plantarum postbiotics in an in vitro model of atopic dermatitis. J Appl Microbiol. 2025 Oct 16:lxaf256. |
Background
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7)-like cytokine primarily expressed by epithelial cells such as keratinocytes. The human TSLP cDNA encodes a 159-amino acid precursor protein containing a 28-amino acid signal peptide. TSLP exhibits dual core functions: on one hand, it plays a key role in initiating type 2 immune responses by acting on its most well-characterized target cells—CD11c+ dendritic cells. It promotes TH2 cell responses and directly enhances the effector functions of CD4+ TH2 cells and basophils, thereby driving the allergic inflammation associated with diseases such as atopic dermatitis and asthma. On the other hand, TSLP also contributes to maintaining immune balance, including establishing non-deletional central tolerance, maintaining a non-inflammatory intestinal environment, and limiting pro-inflammatory cytokines. Consequently, TSLP serves as a pivotal molecular link between the epithelial barrier and the immune system, involved both in host defense against helminth parasites and in the pathogenesis of various inflammatory diseases.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy