SKU: 8251462968

IgG2a Fc (Glu98-Lys330) Protein, Mouse

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Description

IgG2a Fc (Glu98-Lys330) Protein, MouseProduct Specification Species Mouse Synonyms IgG2A Accession P01863 Amino Acid Sequence Glu98 Lys330 EPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK Expression System HEK293 Molecular Weight 29 33kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation

Product Specification


Species Mouse
Synonyms IgG2A
Accession P01863
Amino Acid Sequence

Glu98-Lys330 EPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK

Expression System HEK293
Molecular Weight 29-33kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Hock, Goddard, MacPherson et al.Levels and in vitro functional effects of circulating anti-hinge antibodies in melanoma patients receiving the immune checkpoint inhibitor pembrolizumab. PLoS One (2023) 18 (9), e0290793.

Background

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Some studies have shown that mIgG2a has a greater effect compared with mIgG1 and mIgE in controlling tumor growth in a therapeutic setting.

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Exchange/Return Notes
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SKU: 8251462968

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4.5 ★★★★★
Based on 29 reviews
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Product Reviews
A
Verified Purchase
Amazon Customer
Los Angeles, US
★★★★★ 3
Ehh
Size: Medium, Color: Multicoloured E-(5-pack)
Very thin, still comfy but very thin material. Super soft though. I've worn and washed and they have held up but I won't be repurchasing bc these are so thin
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 14, 2026
G
Verified Purchase
Grma4m&m
Waukegan, US
★★★★★ 5
They’re fantastic!!!!
Size: X-Large, Color: Multicoloured E-(5-pack)
My clothing size is 16/18 and XL. Even though Amazon suggested a size XXL, I ordered my normal XL and they fit perfectly. The fabric for this style is 92% bamboo viscose and is amazingly soft and almost silky feeling. I had ordered a different boy short in this brand but they were 80% bamboo viscose and the fabric was significantly heavier. I returned those and ordered these.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 25, 2026
L
Verified Purchase
Liz Newman
Port Orchard, US
★★★★★ 5
Comfortable and cool. Does not ride up.
Color: 01-multicolour (4-pack), Size: Medium
Extremely comfortable. Stays cool. Ample coverage. Quality material. They do not creep up. I ordered a medium which I generally take a size small. I have reordered and will reorder again to add more colors to my collection.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
J
Verified Purchase
Janola
Lexington, US
★★★★★ 5
Great Value for Cool Thigh Protection
Color: 02-multicolour (4-pack), Size: XX-Large
For the price, I'm not sure there are better women's boxer shortlettes anywhere. I've tried more expensive brands, and for quality and cooling, these are right up there. I have other bamboo viscose undies that still get gross when I get sweaty in the summer, but these, with the large mesh panel, really help wick away a lot of that moisture, keeping you feeling dryer and cooler. I find that the leg openings are comfortable and don't roll up! and the waist band doesn't dig, nor does it roll down. These do not provide any compression, and I wasn't looking for any. I just wanted some cooling, thigh protecting women's boxers that wouldn't break the bank. These are them! Bonus- I've washed them and put them in the dryer (following their instructions), and they haven't shrunk; they look about the same and are nice and soft.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 28, 2025
R
Verified Purchase
Reviewer
Charlottesville, US
★★★★★ 4
Great for the entire family but expensive
So far so good. The brand of boxers we had been buying changed their style and construction so we needed to find an alternative. These have held up well so far to multiple weeks of frequent washing and wearing from the entire family. We did size up from the usual 6/M we normally buy and ordered large to prevent the legs from rolling up which worked out great. Our daughter likes the length and how soft the fabric is for wearing under skirts and gym shorts and liners stay put without moving or leaking as another reviewer mentioned. Our son says they are comfortable and fit well being just supportive enough without being constrictive. We all agree that there seems to be not enough fabric in the back as they tend to be much tighter across the backside than the front and that also causes the waist band to ride lower in the back than the front. These have better seam placement than some brands we tried with no seam across the lady bits and no seam down the middle of the back side so they are more much comfortable but the cost is also much higher and that is why we're only giving it 4 stars. These will stay in the rotation until we find something cheaper that both us and the kids like.
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Reviewed in the United States on January 24, 2026

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