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Description
Human GZMB , His tagProduct Specification Species Human Synonyms C11, CTLA 1, Cathepsin G like 1 (CTSGL1), Cytotoxic T lymphocyte proteinase 2 (Lymphocyte protease), Fragmentin 2, Granzyme 2, Human lymphocyte protein (HLP), SECT, T cell serine protease 1 3E, CGL1, CSPB, GRB Accession P10144 Amino Acid Sequence Protein sequence(P10144, Gly19 Tyr247, with C 10*His)
Product Specification
| Species | Human |
| Synonyms | C11, CTLA-1, Cathepsin G-like 1 (CTSGL1), Cytotoxic T-lymphocyte proteinase 2 (Lymphocyte protease), Fragmentin-2, Granzyme-2, Human lymphocyte protein (HLP), SECT, T-cell serine protease 1-3E, CGL1, CSPB, GRB |
| Accession | P10144 |
| Amino Acid Sequence | Protein sequence(P10144, Gly19-Tyr247, with C-10*His) GEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRYGGGGSHHHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | Theoretical:27.4kDa Actual:33kDa |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, 1mM EDTA, pH7.4. |
| Reconstitution | Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation. |
| Stability & Storage | 12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles. |
Background
Granzyme B (GZMB) is one of the serine protease granzymes most commonly found in the granules of natural killer cells (NK cells) and cytotoxic T cells. It is secreted by these cells along with the pore forming protein perforin to mediate apoptosis in target cells.Granzyme B has also been found to be produced by a wide range of non-cytotoxic cells ranging from basophils and mast cells to smooth muscle cells. The secondary functions of granzyme B are also numerous. Granzyme B has shown to be involved in inducing inflammation by stimulating cytokine release and is also involved in extracellular matrix remodelling.
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Product Reviews
★★★★★ 5
Fit perfect, easy to install.
Size: 24" + 19"(Pair for Front Windshield Lock)
Excellent replacement wiper blades. Easy to install, fit my 2023 Honda Civic perfectly.
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Reviewed in the United States on March 27, 2026
★★★★★ 5
Great
Size: 24" + 19"(Pair for Front Windshield Lock)
Way cheaper than buying local and come in a set work great
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Reviewed in the United States on March 18, 2026
★★★★★ 5
Seriously good wipers
Size: 24" + 19"(Pair for Front Windshield Lock)
These things are awesome. I'd say they are on par with what comes on the car from factory.
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Reviewed in the United States on April 16, 2026
★★★★★ 5
Limpia l
Size: 24" + 19"(Pair for Front Windshield Lock)
Excelentes en temporada de lluvia me han sido útiles
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Reviewed in the United States on May 25, 2026
★★★★★ 5
Perfect fit for my 2018 Civic—easy, affordable, and worth it
Size: 9.5" x 10.9" x 2.1"
I’ve bought this cabin air filter multiple times for my 2018 Honda Civic, and it’s consistently great quality. It fits perfectly and is super easy to install—takes just a few minutes to swap out, and I always do it myself. Way cheaper than going to a shop or dealership. The airflow is smooth, there’s no smell at all, and it keeps the inside of my car feeling clean and fresh. No weird odors, no dust blowing in—just a solid, dependable filter that does its job well. This is the only one I’ll keep buying.
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Reviewed in the United States on May 11, 2025