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Description
Fibronectin-CH296 Protein, HumanProduct Specification Species Human Synonyms Fibronectin, FN, CIG, FNZ, MSF Accession P02751 15 Amino Acid Sequence Pro1361 Ser1637&Ala1812 Thr2107 Expression System E. coli Molecular Weight 58kDa (Reducing) Purity 95% by SDS PAGE& HPLC Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer 20mM Tris, 200mM NaCl, 5% Trehalose, 0. 02% Tween 20, pH8. 5 Reconstitution Reconstitute at 0. 1 1 mg ml
Product Specification
| Species | Human |
| Synonyms | Fibronectin, FN, CIG, FNZ, MSF |
| Accession | P02751-15 |
| Amino Acid Sequence | Pro1361-Ser1637&Ala1812-Thr2107 |
| Expression System | E.coli |
| Molecular Weight | 58kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE& HPLC |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20mM Tris, 200mM NaCl, 5% Trehalose, 0.02% Tween-20, pH8.5 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | Zhou Y. et al. (2020) The effect and clinical significance of FN1 expression on biological functions of gastric cancer cells. Cell Mol Biol (Noisy-le-grand). 66(5): 191-198. |
Background
FN (Fibronectin) is a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. It is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. In recent years, FN has been shown to play an important role in the regulation of various malignant tumors such as lung cancer, colorectal cancer, and ovarian cancer.
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