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Description
IgG2b Fc Protein, LlamaProduct Specification Species llama Synonyms Ig gamma 2 chain C region,IgG2B Fc Accession AAX73259. 1 Amino Acid Sequence EPKTPKPQPQPQPQPNPTTESKCPKCPAPELLGGPSVFIFPPKPKDVLSISGRPEVTCVVVDVGQEDPEVSFNWYIDGAEVRTANTRPKEEQFNSTYRVVSVLPIQHQDWLTGKEFKCKVNNKALPAPIEKTISKAKGQTREPQVYALAPHREELAKDTVSVTCLVKGFYPPDINVEWQRNRQPEPEGTYATTPPQLDNDGTYFLYSKLSVGKNTWQRGETFTCVVMHETLHNHYTQKSISQS Expression System HEK293 Molecular Weight 35 40kDa(Reducing) Purity 95%, by SDS PAGE
Product Specification
| Species | llama |
| Synonyms | Ig gamma-2 chain C region,IgG2B Fc |
| Accession | AAX73259.1 |
| Amino Acid Sequence | EPKTPKPQPQPQPQPNPTTESKCPKCPAPELLGGPSVFIFPPKPKDVLSISGRPEVTCVVVDVGQEDPEVSFNWYIDGAEVRTANTRPKEEQFNSTYRVVSVLPIQHQDWLTGKEFKCKVNNKALPAPIEKTISKAKGQTREPQVYALAPHREELAKDTVSVTCLVKGFYPPDINVEWQRNRQPEPEGTYATTPPQLDNDGTYFLYSKLSVGKNTWQRGETFTCVVMHETLHNHYTQKSISQS |
| Expression System | HEK293 |
| Molecular Weight | 35-40kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, -20 to -70 °C as supplied. |
Background
Immunoglobulin G (IgG) is a kind of monomer immunoglobulin which is developed and secreted by effective B cells and participates in secondary antibody reaction. IgG has four subclasses (IgG1,IgG2,IgG3,IgG4). IgG2 contains two members: IgG2a and IgG2b, both of which belong to the Fc fragments of IgG antibodies. Fc fragments have been shown to mediate phagocytosis, trigger inflammation, and target immunoglobulin Ig to specific tissues. In addition, some studies have shown that protein G or protein An on the surface of some staphylococci and Streptococcus strains can also specifically bind to the Fc region.
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