SKU: 83859169597

TNF-R2 Recombinant Rabbit mAb (SDT-2099-441)

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Description

TNF-R2 Recombinant Rabbit mAb (SDT-2099-441)Product Specification Host Rabbit Antigen TNF R2 Synonyms Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2 (TNF R2); Tumor necrosis factor receptor type II (TNF RII; TNFR II); p75; p80 TNF alpha receptor; CD120b Immunogen Recombinant Protein Accession P20333 Clone Number SDT 2099 441 Antibody Type Recombinant mAb Isotype IgG Application Sandwich ELISA Reactivity Hu Cross Reactivity No cross reactivity against TNF

Product Specification


Host Rabbit
Antigen TNF-R2
Synonyms Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor 2 (TNF-R2); Tumor necrosis factor receptor type II (TNF-RII; TNFR-II); p75; p80 TNF-alpha receptor; CD120b
Immunogen Recombinant Protein
Accession P20333
Clone Number SDT-2099-441
Antibody Type Recombinant mAb
Isotype IgG
Application Sandwich ELISA
Reactivity Hu
Cross Reactivity

No cross-reactivity against TNF-R1
Purification Protein A
Concentration 2 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt, 2 to 8 °C as supplied

Background

TNF-R2, or Tumor Necrosis Factor Receptor 2 (also known as CD120b), is a membrane-bound receptor primarily expressed on immune and endothelial cells. It binds to TNF-alpha, a key inflammatory cytokine, but transmits different signals than the related TNF-R1. TNF-R2 activation generally promotes cell survival, proliferation, and immunoregulatory functions. Detection of TNF-R2, particularly its soluble form (sTNF-R2) shed into the bloodstream, has significant clinical importance. Measuring sTNF-R2 levels via techniques like ELISA serves as a stable biomarker for overall TNF system activity. Elevated levels indicate chronic inflammatory and immune activation, correlating with disease severity in conditions like rheumatoid arthritis, sepsis, and certain cancers. Its detection aids in monitoring disease progression and therapeutic response, offering insights into the inflammatory state more reliably than fluctuating TNF-alpha itself.

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Exchange/Return Notes
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SKU: 83859169597

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4.5 ★★★★★
Based on 16 reviews
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M
Verified Purchase
Mimi D.
Bozeman, US
★★★★★ 5
A rich moisturizer that doesn’t feel heavy!
Size: 13.5 Ounce (Pack of 1)
I bought this because the skin on my face is very reactive and has also been very dry and I wanted to try something that was a little more rich than the moisturizer I was using. I liked that this is for face and body so it comes in a bigger size than typical face moisturizers come in. I have been using it for about a week and have noticed a reduction in flakiness and my sensitive skin does not get irritated by it. It absorbs really well and doesn’t feel heavy or make my skin feel sticky. I definitely feel it is worth the price since you get so much in the bottle and it will last a very long time!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
V
Verified Purchase
Verified User
Omaha, US
★★★★★ 5
The best eczema cream I’ve used !!!
Size: 6.76 Ounce (Pack of 1)
I will give 10 stars if it were available!! Used most of the eczema creams out there, including prescribed ointments, but given the fact you can’t avoid using water on your hands throughout the day, the eczema was only getting worse for the past couple of months! I am glad I didn’t give up and found this cream!!! The second I put this cream on my hands, it immediately moisturized the itching and flaking skin without drying or being greasy unlike other creams I’ve used before. It’s very calming, soothing, and deeply moisturizing! So I had to write this review for those who are suffering the similar symptoms. This may help you as much as it is helping me as I speak!
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Reviewed in the United States on May 5, 2026
M
Verified Purchase
Megan
San Leandro, US
★★★★★ 4
Seems to work for damaged barrier (accidental damage as well as eczema and rosacea).
Size: 6.76 Ounce (Pack of 1)
SO I am currently tryign to repair a damaged skin barrier. I have both rosacea and eczema so it's nearly impossible to find a product that makes both conditions happy. I started out using the cream version of this but my face always felt dry with it. I decided to try this since a balm usually helps keep in moisture much better. I am only using a gentle cleanser and this, planning on adding in a toner at some point. At first I thought I was sent the cream again because this comes out like their cream version but as you rub it to spread, you can tell it has a thicker feel to it. It spreads easily and doesn't tug at my skin. Seems to sink in pretty quickly but it does leave a sticky film until it completely absorbs. I can feel my eyelids stick while waiting. Not sure how long it takes to fully absorb because once it does on my eyelids, I forget. But the stickiness does go away and leaves a soft texture behind. I do find some itching in places I normally get when my skin dislikes an ingredient. But I'm not sure if it's my normal or current damaged barrier. It helps with the dry feeling and I would say I only feel a slight tightness. But so far, the best moisturizer I have used. And I love that there is NO NIACINAMIDE, NO HYALURONIC ACID, no oat, no shea butter, and no cica/centella asiatica. These ingredients wreak havoc on my skin and everybody is adding this to everything. It's been so hard to find a moisturizer.
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Reviewed in the United States on September 18, 2025
G
Verified Purchase
GAIL SUTHERLAND
Boise, US
★★★★★ 5
Works quickly to calm itch
Size: 6.76 Ounce (Pack of 1)
I had an itchy outbreak on the back of my hand the day this product arrived. Perfect timing. Applied Avene and within a short time the itch calmed almost 100%. Slept through the night and this morning, the red rash is about 95% healed. So glad I bought this. Just another old age issue to deal with.
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Reviewed in the United States on May 21, 2026
M
Verified Purchase
M. Gondek
Grantham, US
★★★★★ 5
Excellent for my sensitive skin and rosacea
Another excellent product from this brand. I have type 1 rosacea on my cheeks, even when I avoid triggers (like red wine, warm weather, etc.), and very sensitive skin overall. I've been using the cicalfate serum from this brand for the sensitivity, but it didn't help the redness. After two weeks of using this twice daily, I noticed a significant difference. After a month, I had no redness unless I encountered a trigger. Even then, the intensity of the redness seemed less. I tried going without this product for a month when the first bottle ran out, and sadly, the redness started coming back within a cycle of weeks. I've got this on auto-delivery now, along with the cicalfate serum. I never want to be without it!
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Reviewed in the United States on October 29, 2025

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