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Description
Claudin 9 Recombinant Rabbit mAb (S-2849-16)Product Specification Host Rabbit Antigen Claudin 9 Synonyms Claudin 9; CLDN9 Immunogen Synthetic Peptide Location Cell membrane Accession O95484 Clone Number S 2849 16 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu Positive Sample MCF7 Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12
Product Specification
| Host | Rabbit |
| Antigen | Claudin 9 |
| Synonyms | Claudin-9; CLDN9 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | O95484 |
| Clone Number | S-2849-16 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu |
| Positive Sample | MCF7 |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:250 | Hu |
| IHC-P | 1:1000 | Hu |
Background
Claudin-9 is a 211-amino-acid tetraspan tight-junction protein that seals the paracellular space between epithelial and endothelial cells while selectively controlling ion and solute permeability; it is highly expressed in the inner ear, lung, testis and epidermis, where its absence or mutation causes deafness, skin barrier defects and increased susceptibility to viral entry, and its transcription is driven by grainyhead-like transcription factors that bind a conserved 5′-enhancer, making claudin-9 a critical determinant of tissue-specific barrier integrity, ion homeostasis and innate defense.
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