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Description
FGF-R1/CD331 His Tag Protein, HumanProduct Specification Species Human Synonyms bFGF R 1 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR 1 Protein, FLG Protein, FLT 2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, HRTFDS Protein, KAL2 Protein, N SAM Protein, OGD Protein Accession P11362 7 Amino Acid Sequence Arg22 Ile376, with C terminal His Expression System HEK293 Molecular Weight 60 70 kDa(Reducing) Purity 95%, by SDS PAGE under reducing conditions
Product Specification
| Species | Human |
| Synonyms | bFGF-R-1 Protein, BFGFR Protein, CD331 Protein, CEK Protein, FGFBR Protein, FGFR-1 Protein, FLG Protein, FLT-2 Protein, FLT2 Protein, HBGFR Protein, HH2 Protein, HRTFDS Protein, KAL2 Protein, N-SAM Protein, OGD Protein |
| Accession | P11362-7 |
| Amino Acid Sequence | Arg22-Ile376, with C-terminal His |
| Expression System | HEK293 |
| Molecular Weight | 60 -70 kDa(Reducing) |
| Purity | ＞95%, by SDS-PAGE under reducing conditions |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4, 5% trehalose |
| Reconstitution | Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation . |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
FGF-R1, fibroblast growth factor receptor 1, also known as CD331, is a receptor tyrosine kinase whose ligand is a specific member of the fibroblast growth factor family. FGF-R1 is a full-length representative protein, which consists of an extracellular domain, three immunoglobulin-like domains, a hydrophobic transmembrane fragment and a cytoplasmic tyrosine kinase domain. The extracellular domain of FGF-R1 interacts with specific extracellular fibroblast growth factors, initiating a series of downstream signals and affecting cell mitosis and differentiation. FGF-R1 protein is considered to play an important role in the development of nervous system. The protein may also help regulate the growth of long bones, such as large bones in the arms and legs.
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