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Description
Keratin 20 Recombinant Rabbit mAb (SDT-013-18)Product Specification Host Rabbit Antigen Keratin 20 Synonyms CK 20, KRT20 Immunogen Synthetic Peptide Location Membrane Accession P35900 Clone Number SDT 013 18 Antibody Type Rabbit mAb Application WB, IHC P, ICC Reactivity Hu Predicted Reactivity Cz Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Rabbit |
| Antigen | Keratin 20 |
| Synonyms | CK-20, KRT20 |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P35900 |
| Clone Number | SDT-013-18 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC |
| Reactivity | Hu |
| Predicted Reactivity | Cz |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:500-1:1000 | |
| WB | 1:1000 | |
| ICC | 1:500 |
Background
Keratin 20, often abbreviated CK20, is a protein that in humans is encoded by the KRT20 gene. Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. In immunohistochemistry, antibodies to CK20 can be used to identify a range of adenocarcinoma arising from epithelia that normally contain the CK20 protein. For example, the protein is commonly found in colorectal cancer, transitional cell carcinomas and in Merkel cell carcinoma, but is absent in lung cancer, prostate cancer, and non-mucinous ovarian cancer. It is often used in combination with antibodies to CK7 to distinguish different types of glandular tumour.
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