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Description
S-RMab® CD38 Recombinant Rabbit mAb (SDT-031-45-2)Product Specification Host Rabbit Antigen CD38 Synonyms 2' phospho ADP ribosyl cyclase, 2' phospho ADP ribosyl cyclase 2' phospho cyclic ADP ribose transferase,2' phospho cyclic ADP ribose transferase,ADP ribosyl cyclase 1 (ADPRC 1),Cyclic ADP ribose hydrolase 1 (cADPr hydrolase 1),T10 Immunogen Synthetic Peptide Location Membrane Accession P28907 Clone Number SDT 031 45 2 Antibody Type Rabbit mAb Application WB, IHC P, ICC, FC Reactivity Hu
Product Specification
| Host | Rabbit |
| Antigen | CD38 |
| Synonyms | 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1 (ADPRC 1),Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1),T10 |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P28907 |
| Clone Number | SDT-031-45-2 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, FC |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 0.05mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| FC | 1:50 | null |
| IHC-P | 1: 500-1:1000 | null |
| WB | 1:500 | null |
| ICC | 1:50 | null |
Background
CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications including social amnesia possibly related to autism. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism, as well as some genetically determined conditions.
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