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Description
Tau (phospho T205) Recombinant Rabbit mAb (SDT-2034-24)Product Specification Host Rabbit Antigen Tau (phospho T205) Synonyms p Tau205, pTau205 Immunogen Synthetic Peptide Clone Number SDT 2034 24 Antibody Type Recombinant mAb Isotype IgG Application CLIA, Sandwich ELISA Reactivity Hu Predicted Reactivity Ms Cross Reactivity No cross reactivity against total Tau, p Tau181, p Tau217, p Tau231. Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | Tau (phospho T205) |
| Synonyms | p-Tau205, pTau205 |
| Immunogen | Synthetic Peptide |
| Clone Number | SDT-2034-24 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Predicted Reactivity | Ms |
| Cross Reactivity | No cross-reactivity against total Tau, p-Tau181, p-Tau217, p-Tau231. |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
Serum and CSF p-tau205 is a highly specific biomarker of AD, exhibiting a continuous and steep increase along with AD progression. Most importantly, it accurately reflects in vivo tau burden, thereby suggesting its potential usefulness identifying and staging tau pathology in AD. Thus, a high throughput method such as the digital immunoassays using pTau205 antibody and total tau antibody as sandwich pairs would be of great use in clinical settings and clinical trials.
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