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Description
GDNF Protein, RatProduct Specification Species Rat Synonyms Glial Derived Neurotrophic Factor,ATF 1 Accession Q07731 Amino Acid Sequence Ser78 Ile211 Expression System E. coli Molecular Weight Approximately 29. 8 kDa, a homodimeric protein consisting of two 134 amino acid non glycosylated polypeptide chains. Purity 97% by SDS PAGE or HPLC. Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer 20 mM PB, with 150 mM NaCl, 0. 05% (v v)
Product Specification
| Species | Rat |
| Synonyms | Glial-Derived Neurotrophic Factor,ATF-1 |
| Accession | Q07731 |
| Amino Acid Sequence | Ser78-Ile211 |
| Expression System | E.coli |
| Molecular Weight | Approximately 29.8 kDa, a homodimeric protein consisting of two 134 amino acid non-glycosylated polypeptide chains. |
| Purity | ＞97% by SDS-PAGE or HPLC. |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20 mM PB, with 150 mM NaCl, 0.05% (v/v) Tween-20, pH 7.4. |
| Reconstitution | Before use this product, please read the direction below carefully. This vial must be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in a sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | For long term storage, the product should be stored ≤ -20℃. |
Background
Glial cell-derived neurotrophic factor is a founding member of the GDNF family of ligands (GFL) and has been shown to interact with GFRA2 and GDNF family receptor alpha 1. It is a small protein that potently promotes the survival and morphological differentiation of various neuronal. It may also modulate local neuronal effects in distal regions of the motor neuron. Recombinant rat GDNF is a homodimeric protein consisting of two 134 amino acid non-glycosylated polypeptide chains and it shares 99% and 93% a.a. sequence identity with murine and human GDNF.
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