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Description
PE Rabbit Anti-Human CD14 Antibody (S-395-8)Product Specification Host Rabbit Antigen CD14 Synonyms Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell specific leucine rich glycoprotein Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession P08571 Clone Number S 395 8 Antibody Type Recombinant mAb Isotype IgG Application FCM Reactivity Hu Positive Sample human peripheral blood cells Purification Protein A Concentration 0. 02mg ml Conjugation PE Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | CD14 |
| Synonyms | Monocyte differentiation antigen CD14; My23 antigen; Myeloid cell-specific leucine-rich glycoprotein |
| Immunogen | Synthetic Peptide |
| Location | Secreted, Cell membrane |
| Accession | P08571 |
| Clone Number | S-395-8 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | human peripheral blood cells |
| Purification | Protein A |
| Concentration | 0.02mg/ml |
| Conjugation | PE |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD14 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein primarily expressed on monocytes, macrophages, and some granulocytes. It functions as a pattern recognition receptor (PRR) and plays a crucial role in the innate immune response by recognizing bacterial lipopolysaccharides (LPS), pathogen-associated molecular patterns (PAMPs), and damage-associated molecular patterns (DAMPs). CD14 exists in two forms: membrane-bound CD14 (mCD14) and soluble CD14 (sCD14), which can be secreted by activated cells. It acts as a co-receptor for Toll-like receptor 4 (TLR4) and enhances the immune response to LPS by facilitating its delivery to the TLR4-MD2 complex. Additionally, CD14 is involved in TLR4-independent signaling pathways and contributes to tissue homeostasis by promoting the clearance of apoptotic cells.
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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4.1 ★★★★★
Based on 9 reviews
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Product Reviews
★★★★★ 5
Best
Size: 10, Color: Espresso II/Black
The best flop ever made
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Reviewed in the United States on May 20, 2026
★★★★★ 5
Best flip-flops I've met
Size: 11, Color: Black/Geyser
Right away I was impressed by the thichness and cushioning of these flip-flops. They are not a flimsy piece of rubber under my foot. The sole is more like that of an athletic shoe with layers and an impressive tread.
I've always found that my heel sits too much on the back edge of flip-flops, or even over it. So I ordered these just a half size large and they're perfect. The foot cradling allows my heel to sit down inside the flip-flop comfortably and securely. They're not about to fall off. The toe piece (I don't know what it's actually called) is not just the typical round rubber post. On these flip-flops it's nicely shaped and fits comfortably between my toes.
The arch support is nice too. They're not just flat.
In spite of being more substantial than the cheapies we all know, these remain lightweight. They clearly look better too
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Reviewed in the United States on April 28, 2026
★★★★★ 5
Well made
Size: 11, Color: Black/Geyser
The first thing that stands out about the Columbia PFG Castback Flip sandals is the solid build and clean fishing-inspired design. The Black/Geyser color combination looks sharp and matches the product photos well. The straps feel durable and comfortable against the foot, and the footbed has a slightly cushioned feel that makes them comfortable right out of the box. Overall construction feels sturdy, which is what you’d expect from something designed for outdoor or water use.
In everyday wear, the sandals are comfortable and easy to walk in. The footbed provides decent grip and support, and the textured surface helps keep your foot from sliding around when they get wet. They work well for casual use, whether it’s around the house, at the beach, or after a day on the water. The lightweight feel also makes them easy to pack for trips or outdoor activities.
After wearing them for a while, they hold up well and remain comfortable for daily use. The materials seem durable and the straps stay secure without stretching out. They’re simple, reliable sandals that work well for warm weather, boating, or casual summer wear. Overall, they’re a solid choice for anyone looking for comfortable flip flops with a slightly more rugged outdoor style.
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Reviewed in the United States on March 10, 2026
★★★★★ 5
Extremely comfortable with slight roomy fit
Size: 11, Color: Black/Geyser, Size: 11, Color: Black/Geyser
These are easily the most comfortable flip flops I have ever owned. From the moment I put them on, there was no break in period at all. They felt soft, supportive, and ready for all day wear right out of the box.
The cushioning is excellent without feeling too soft, and they have a nice stable feel when walking. They are lightweight and clearly made with quality materials, making them great for everyday use or around water.
One thing to note is that they run a little on the larger side, so if you are between sizes, you may want to consider sizing down for a better fit.
Overall, these are a great combination of comfort, durability, and function. I would absolutely recommend them, especially if comfort is your top priority. (Excuse the teeth marks- my dog unfortunately got ahold of them before I snapped the photo- they are PERFECT out of the box)
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Reviewed in the United States on March 22, 2026
★★★★★ 5
Comfortable Flip-Flops with a Clean, Sporty Look
Size: 13, Color: Black/Geyser
I picked up the Columbia Men’s PFG Castback Flip in the black and white colorway, and the first thing I noticed was how comfortable they felt right out of the box.
How They’ve Been Used:
Even though it’s still winter, I’ve been wearing them around the house occasionally to get a feel for the fit and comfort. I plan to use them more regularly outdoors once the weather warms up.
What Worked Well:
Immediate Comfort: The footbed feels cushioned and supportive without needing a break-in period.
Secure Fit: The straps sit comfortably without rubbing or feeling stiff.
Lightweight Design: Easy to slip on and off for quick wear.
Clean Style: The black and white combination gives them a sharp, versatile look.
Positive Feedback: My wife has already commented on how good they look.
Things to Keep in Mind:
Seasonal Use: Best suited for warmer weather and casual settings.
Sizing: Checking the size guide helps ensure the right fit.
Bottom Line:
Based on my experience so far, these flip-flops offer a great balance of comfort and style. They’re comfortable enough for everyday wear and look sharp enough for casual outings. I’m looking forward to putting them to full use once spring arrives.
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Reviewed in the United States on February 27, 2026
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