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Description
Human Transthyretin/Prealbumin OneStep ELISA KitProduct Specification Antigen Prealbumin Immunogen Recombinant Protein Antibody Type Recombinant mAb Reactivity Hu Purification Protein A Stability & Storage 12 months from date of receipt reconstitution, 2 to 8'C as supplied. Kit Precision Intra assay: 3. 6% Inter assay: 8. 5% Sample type Cell culture supernatant, Serum, Plasma Assay type Sandwich (quantitative) Sensitivity 6. 655 pg mL Range 15. 63 pg mL 1000 pg mL Recovery Cell culture supernatant:
Product Specification
| Antigen | Prealbumin |
| Immunogen | Recombinant Protein |
| Antibody Type | Recombinant mAb |
| Reactivity | Hu |
| Purification | Protein A |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8'C as supplied. |
Kit
| Precision | Intra-assay: 3.6%； Inter-assay: 8.5% |
| Sample type | Cell culture supernatant, Serum, Plasma |
| Assay type | Sandwich (quantitative) |
| Sensitivity | 6.655 pg/mL |
| Range | 15.63 pg/mL – 1000 pg/mL |
| Recovery | Cell culture supernatant: 88% Serum: 87% Plasma-Heparin: 92% |
| Assay time | 60 minutes |
| Species reactivity | Hu |
Background
Human Prealbumin, now more commonly referred to as Transthyretin (TTR), is a transport protein primarily synthesized in the liver and the choroid plexus of the brain. It serves two major physiological functions: transporting thyroxine (T4) and forming a complex with retinol-binding protein to carry vitamin A. Notably, it has a short half-life of approximately 2 days, making it a highly sensitive and early indicator of acute nutritional status and systemic inflammation, often measured clinically to assess malnutrition, particularly in conditions like cirrhosis, inflammation, or critical illness. Additionally, certain genetic mutations in the TTR gene can lead to its misfolding and aggregation, resulting in hereditary amyloidosis, a serious disease where amyloid fibrils accumulate in tissues such as the heart and nerves.
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