SKU: 95269495461

BID Protein, Huamn

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Description

BID Protein, HuamnProduct Specification Species Human Synonyms BH3 Interacting Domain Death Agonist; p22 BID; BID Accession P55957 Amino Acid Sequence Met1 Asp195 Expression System E. coli Molecular Weight 21. 99 KDa Purity >95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Liquid Storage Buffer 20mM PB, 100mM KCl, pH 7. 4. Stability & Storage Store at 70C, stable for 6 months after receipt. Store at 70C, stable for 3 months under

Product Specification


Species Human
Synonyms BH3-Interacting Domain Death Agonist; p22 BID; BID
Accession P55957
Amino Acid Sequence

Met1-Asp195

Expression System E.coli
Molecular Weight

21.99 KDa

Purity

>95% by SDS-PAGE

Endotoxin <1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Liquid
Storage Buffer 20mM PB, 100mM KCl, pH 7.4.
Stability & Storage
  • Store at ≤-70°C, stable for 6 months after receipt.
  • Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
  • Please minimize freeze-thaw cycles.


Background

BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint.

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SKU: 95269495461

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4.5 ★★★★★
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GET SOME!
Waukegan, US
★★★★★ 5
Feels refreshing on the head…
Color: Black
I purchased a few of these on UA application. However, when I decided to put some more the UA app was out of stock. I love the skull caps!! I use them for the gym and for work. They’re very comfortable and outstanding if you’re in a hot environment, sweat a lot or just want to be cooler. They haven’t slipped at all and it’s great value for what I spent! So far I have seven in total. I may purchase three more shortly before summer hits that way I can use one at the gym and one at work per day and don’t have to worry about doing my laundry just to have clean skull caps.
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Reviewed in the United States on February 2, 2026
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Verified Purchase
Amazon Customer
Dallas, US
★★★★★ 5
The perfect sock!
Size: 6-10, Color: Halo Gray/Assorted
The only socks that I can wear with my hey dudes. They stay on my ankles and never slid down into the shoe. I will forever order these as long as they are available. They are comfy too!
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Reviewed in the United States on August 21, 2025
R
Verified Purchase
Ryan S
Alexandria, US
★★★★★ 5
Good option, especially in warmer weather
Size: 6-10, Color: Black
High quality socks and very durable. Nice touch adding the grip on the back of the ankle so the sock stays up. Size is a true fit to the size of your foot as well.
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Reviewed in the United States on April 17, 2025
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Verified Purchase
Patricia
West Palm Beach, US
★★★★★ 5
Love these socks!
Size: 6-10, Color: White
Comfortable, no show, and most importantly The Do No Slip!!!! I keep coming back to add to my supply because they have become the only sock I wear. I’ve been using them for a couple years now and they hold to great to washing, bleaching and the dryer. Highly recommended.
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Reviewed in the United States on July 24, 2024
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BoyMom
Pawtucket, US
★★★★★ 5
The only socks I will buy
Size: 6-10, Color: Halo Gray/Assorted
These are hands down my favorite socks to wear with tennis shoes. Bought my original 6 pack in the store, liked them so much I went buy more and they were gone. These don't slip on your heel like most socks do. Come up high enough on the top of your foot to protect from tongue rubbing (I giggled when I wrote that) and they come in fun colors. Love they are ultra no show and provide padding but people can't see them with shoes on. Five stars!
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Reviewed in the United States on January 12, 2023

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