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Description
Myosin light chain 3 Recombinant Rabbit mAb (S-664-75)Product Specification Host Rabbit Antigen Myosin light chain 3 Synonyms Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow twitch muscle B ventricular isoform, MLC1SB, Ventricular myosin alkali light chain, Ventricular myosin light chain 1, VLCl, Ventricular slow twitch myosin alkali light chain, MLC lV sb, MYL3 Immunogen Synthetic Peptide Location Cytosol Accession P08590 Clone Number S 664 75 Antibody Type Recombinant mAb Isotype IgG
Product Specification
| Host | Rabbit |
| Antigen | Myosin light chain 3 |
| Synonyms | Cardiac myosin light chain 1, CMLC1, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Ventricular myosin alkali light chain, Ventricular myosin light chain 1, VLCl, Ventricular/slow twitch myosin alkali light chain, MLC-lV/sb, MYL3 |
| Immunogen | Synthetic Peptide |
| Location | Cytosol |
| Accession | P08590 |
| Clone Number | S-664-75 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:2000 |
Background
Myosin essential light chain (ELC), ventricular/cardiac isoform is a protein that in humans is encoded by the MYL3 gene. This cardiac ventricular/slow skeletal ELC isoform is distinct from that expressed in fast skeletal muscle (MYL1) and cardiac atrial muscle (MYL4). Ventricular ELC is part of the myosin molecule and is important in modulating cardiac muscle contraction. Mutations in MYL3 have been identified as a cause of familial hypertrophic cardiomyopathy, and associated with a mid-left ventricular chamber type hypertrophy.
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