SKU: 97607853621

ADAM8 Recombinant Rabbit mAb (S-2546-23)

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Description

ADAM8 Recombinant Rabbit mAb (S-2546-23)Product Specification Host Rabbit Antigen ADAM8 Synonyms Disintegrin and metalloproteinase domain containing protein 8; Cell surface antigen MS2; CD156a; MS2 Immunogen Recombinant Protein Location Membrane Accession P78325 Clone Number S 2546 23 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu Positive Sample MDA MB 231, Capan 1, BxPC 3 Purification Protein G Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance

Product Specification


Host Rabbit
Antigen ADAM8
Synonyms Disintegrin and metalloproteinase domain-containing protein 8; Cell surface antigen MS2; CD156a; MS2
Immunogen Recombinant Protein
Location Membrane
Accession P78325
Clone Number S-2546-23
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu
Positive Sample MDA-MB-231, Capan-1, BxPC-3
Purification Protein G
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu

Background

ADAM8 (a disintegrin and metalloproteinase domain 8), also designated CD156a, is a type-I transmembrane metalloproteinase encoded at 10q26.3 that belongs to the ADAM family of cell-surface sheddases; its modular architecture comprises a pro-domain, catalytic metalloprotease, disintegrin-like, cysteine-rich, EGF-like, transmembrane, and cytoplasmic tail domains, endowing it with the dual capacity to cleave extracellular-matrix proteins such as fibronectin and collagen while simultaneously regulating cell–cell and cell–matrix interactions through its disintegrin motif. Physiologically, ADAM8 is expressed at highest levels in immune and neuronal tissues, where it modulates leukocyte transmigration, cytokine and chemokine shedding (e.g., TNF-α, CX3CL1), and neuronal adhesion during development and repair; pathologically, its marked up-regulation in cancers promotes epithelial-to-mesenchymal transition, angiogenesis, and metastasis by attenuating intercellular adhesion and degrading matrix barriers, and in allergic asthma it orchestrates airway remodeling and hyper-responsiveness, rendering ADAM8 a prognostic biomarker and an attractive therapeutic target for anti-metastatic and anti-inflammatory interventions .

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SKU: 97607853621

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4.9 ★★★★★
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Kristen
Chelsea, US
★★★★★ 5
Love these
Size: 80 Count (Pack of 3)
I love these for my toddler, they are bigger than regular wipes and have a soft side and a scrubbing side made with raised dots that are still soft on the skin. They are wet enough to do a great job and I like that there is no alcohol. Great value for the price and really sturdy quality. Diaper rash has lessened since we switched to these. I've ordered several times. Easy to use.
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Reviewed in the United States on December 20, 2025
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Verified Purchase
Wendy, NY
Waukegan, US
★★★★★ 5
Thick and big wipes
Size: 80 Count (Pack of 3)
Great quality and very moist. Great for cleaning up after a baby
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Reviewed in the United States on May 25, 2026
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Verified Purchase
lola
Waukegan, US
★★★★★ 5
Best wipes I’ve ever used
Size: 10 Count (Pack of 6)
The price was so affordable I thought I might be disappointed. I’ve tried maybe 5 other brands and this is by FAR the best wipes and in perfect packaging for in home and travel use. The wipes are very thick, they do not break for ANYTHING I’m shocked. No fuzzy stringy debris like other wipes I’ve tried. Great for sensitive skin ! Will continue to buy.
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Reviewed in the United States on March 19, 2026
M
Verified Purchase
Marz
Houston, US
★★★★★ 4
Perfect Travel Wipes!
Size: 10 Count (Pack of 6)
These travel-size baby wipes are so nice! They’re thick, durable, and perfectly moist so you don’t need a bunch at once. Plus, the mini size is super cute and convenient for on-the-go.
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Reviewed in the United States on March 3, 2026
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Jacquelyn Unpingco
West Palm Beach, US
★★★★★ 5
Amazing quality wipes for difficult messes!
Size: 80 Count (Pack of 3)
The quality of these wipes are impeccable! They are thick and super strong with the best texture to help difficult clean ups if you know what I mean. It comes with so much too I swear it took forever to even finish one bag. These will definitely be a keeper in my rotation of baby wipes! If you haven’t tried them u definitely recommend you give them a try at least once to see what I’m talking about!
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Reviewed in the United States on February 26, 2026

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