SKU: 98163552924

APC Rat Anti-Mouse/Human CD45R/B220 Antibody (S-R519)

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Description

APC Rat Anti-Mouse/Human CD45R/B220 Antibody (S-R519)Product Specification Host Rat Antigen CD45R B220 Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); Lymphocyte antigen 5 (Ly 5); T200; CD45; Ly 5; Ptprc Location Cell membrane, Synapse Accession P06800P08575 Clone Number S R519 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Hu, Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 05mg ml Conjugation APC Physical

Product Specification


Host Rat
Antigen CD45R/B220
Synonyms Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); Lymphocyte antigen 5 (Ly-5); T200; CD45; Ly-5; Ptprc
Location Cell membrane, Synapse
Accession P06800、P08575
Clone Number S-R519
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu, Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein G
Concentration 0.05mg/ml
Conjugation APC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu, Ms

Background

CD45R/B220 is an isoform of the CD45 protein, a member of the protein tyrosine phosphatase (PTP) family, and serves as a critical regulator of T- and B-cell antigen receptor signaling. It is predominantly expressed on the surface of B cells, from early pro-B cells to mature and activated B cells, making it a commonly used pan-B cell marker in mice. Additionally, CD45R/B220 is also found on certain subsets of activated T cells, lymphokine-activated killer cells (LAK), NK cell progenitors, and T cells in mutant mice. This molecule plays a crucial role in lymphocyte development and antigen signaling, and its expression is regulated during different stages of B cell maturation.

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SKU: 98163552924

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4.5 ★★★★★
Based on 8 reviews
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M
Verified Purchase
Mommakins
Bozeman, US
★★★★★ 1
Horrible, don't buy
Size: 1.8in for Puppy Dogs
I wanted to love these. They had so much potential. It's a good size. It seems like a good shape. But ... 1) first red flag should have been the packaging. It looked like it was a dollar store item that had beenblost on the shelves for years. 2) the rubber is super flexible. I was expecting it to be sturdier. I can flatten the ball without lich force. Maybe that doesn't matter. Naybe flexible is good. But I never got a chance to test out it's durability against a pup because... 3) it smelled. I expected it to smell like rubber, like most rubber toys. Rubber smell is okay. Usually rubber smell goes away. But, this was NOT a rubber smell. It smells like peppermint or something similar. It's like someone sprayed essential oils when mixing the rubber and now the smell will not leave. I soaked it in dawn soap half the day and overnight. I rubbed. I scrubbed. The smell actually gets worst the more you scrub it!!! It's like a scented marker or scented eraser, but you do NOT want the scent in a dog toy! My dog cannot smell the food in it because the smell of the weird mint-like scent is so overpowering. He saw it had food, and wanted it, but every time he started sniffing wildly, he would recoil. Whoever thought it was a good idea to scent this was WRONG. Mint in the form of an essential oil is extremely poisonous to dogs!! So, why they would put a mint-loke scent ijto the dog's rubber treat toy is beyond me. I would return this if I hadn't throw out the package immediately. I considered pulling the package out of the trash once i realized the scent issue but other trash had already been dumped into the trash can over it and i didn't want to dig through trash. The ball is still soaking in soap. I scrubbed again this morning. I let obe dry out. No luck. It actually seems to get worst the more you scrub, like it really is embedded in the rubber itself. Yuck!!!
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Reviewed in the United States on January 1, 2022
K
Verified Purchase
Karina Z.
Carnegie, US
★★★★★ 5
Perro 🐶 happy
Color: Yellow and Purple
Dior Emocionado con sus chanclas para remorder
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
T
Verified Purchase
TN doc
Natrona Heights, US
★★★★★ 5
Excellent, unless your pup is a dedicated destructo-dog!
Color: Yellow and Orange
I purchased this twice for a young puppy. She loves these slippers, and they are quite resistent to her piranha teeth. The same can't be said for my adult Golden Retriever, who destroys almost every toy; it's one of his missions in life. A slipper accidently found its way to him, and he shredded it within about 45 minutes. I have to say that I'm surprised it lasted that long, attesting to its relative durability. Overall, I recommend these for most dogs.
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Reviewed in the United States on February 20, 2026
A
Verified Purchase
Anm
Fort Morgan, US
★★★★★ 1
Dangerous.
Color: Purple
Died in about 2 days. Dogs chewed it to bits and then tried to swallow the pieces. Would not recommend for pet safety. I don't have big dogs, I have littler puppies (3 and 5 months) - would likely have died instantly with big chewers.
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Reviewed in the United States on December 28, 2025
B
Verified Purchase
Betty Green
Carnegie, US
★★★★★ 3
Disappointed they didn’t hold up long before pieces was being chewed off.
Color: Yellow and Purple
My minature poodle loved them till she started chewing pieces off of them so we had to dispose of them.
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Reviewed in the United States on May 31, 2026

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