Pay in installments of $20.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 30 - Aug 4
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
K9 Advantix II XL Dog Flea, Tick & Mosquito Treatment & PreventionK9 Advantix II Extra Large Dog is the veterinarian recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing
K9 Advantix II Extra Large Dog is the veterinarian-recommended formula that helps defend your dog against five pests: fleas, ticks, mosquitoes, biting flies and lice. And unlike other treatments, K9 Advantix II kills and repels fleas, ticks and mosquitoes. K9 Advantix II topical treatment gets straight to work killing fleas on dogs within 12 hours of initial application. This formula stops existing flea infestations and prevents new ones by killing adult fleas on contact so they can’t lay eggs and they don’t have to bite your dog to die. Fleas, ticks, mosquitoes and other pests not only cause discomfort; they may also transmit disease. Monthly use of K9 Advantix II is important to protect your dog against fleas that may cause transmission of tapeworms. This formula also kills fleas which may cause Flea Allergy Dermatitis and flea bite anemia. That’s why K9 Advantix II Extra Large Dog topical, spot-on formula makes application simple - going on in seconds. It's easier than a flea collar and there are no hard-to-swallow pills. You’ll also love that K9 Advantix II is fragrance-free and waterproof after 24 hours of application. Check the product label for information on application and potential side effects. K9 Advantix II pest protection is effective on both indoor and outdoor dogs. Your dog should be at least 7 weeks old and weigh over 55 lbs. to use K9 Advantix II Extra Large Dog. For the ultimate convenience in care, K9 Advantix II is available over the counter – no prescription needed. And, you can stock up with 2-dose, 4-dose and 6-dose packs so you never miss a monthly treatment. Once K9 Advantix II is applied, your dog is ready to get right back to big-pup cuddles and racing around the park. K9 Advantix II Extra Large Dog is a trademark of Elanco or its affiliates.
Key Features
-
K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
-
Kills fleas within 12 hours of application
-
Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
-
Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
-
No prescription needed
Directions for Use
Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply entire contents of the tube along the top of the dog's back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Storage Instructions
Store in a cool, dry place inaccessible to children and pets. Protect from freezing.
Active Ingredients
Imidacloprid, Permethrin, Pyriproxyfen
Product Form
- Topical
Pet Size
- Extra Large
Pet Lifestage
- 7 weeks and older
Pet Weight
Over 55 lbs
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.0 ★★★★★
Based on 10 reviews
Sort
Product Reviews
★★★★★ 5
Protects floors
Size: X-Large: 28" x 34"
I love these pee pad holders. My dog goes near the edge of the pad and the urine gets on my hardwood floors. With these pads the edges of the pee pad holder catches the urine before it gets on the floors. It is very easy to clean the pad holder. I am so thankful it protects my floors!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 5, 2026
★★★★★ 4
Works well with the pads. Keeps them from getting bunched up all over the floor.
Size: Small: 24" x 24"
It was a nice idea, but my dogs chewed it up. If you don't have a chewer, then it's really nice.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 24, 2025
★★★★★ 5
Saved my sanity
Size: Small: 24" x 24"
I thought I knew everything about cats, but when my 14 year old cat stopped using the litter box, I could not fix it. I did persuade her to start using puppy pads but the problem was she would pee toward the edge and it always got on the floor. Or, defying everything I know about reality, she would find a way to pee UNDER the puppy pad.
I asked ChatGPT for advice and it recommended these. They fixed the problem by 80% and I'll take it! These mats help a ton. She still gets some pee on the floor, but it's not the huge problem it used to be. The edge on the mat keeps it contained. And enzymatic cleaner works its magic on the floor.
The clips that go on the edges are kinda fragile, but that's why they give you extras.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 10, 2026
★★★★★ 1
Not Leak Proof
Size: X-Large: 28" x 34"
horrible do not buy! leaks threw and caused a permanent stain and smell. thought it was good but after a week i noticed the smell and lifted up the mat there was complete pee under.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 12, 2026
★★★★★ 5
Great investment
Size: Small: 24" x 24"
It catches the pee that runs off the pad, great investment!!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 12, 2026
recommand products
HKM-350675 Training Floating Disc for Dogs - Durable Blue Disc, Suitable for Small to Large Dog Puppies, 23cm Diameter
74.99
Long Sleeve Raglan T-Shirt / White / VB FUTSAL
25.00
Long Sleeve Performance Tee / Black / VB Futsal
24.00
HKM-776659 Cute Cat Face Infrared Doumao Pen - Plastic, Lightweight, Available in Blue, Green, Coffee
69.99
Performance Fleece Hooded Sweatshirt (Youth and Adult) / Black / Beach FC
40.00