SKU: 22098370970

NMN 1000+ (Previously NAD SUPPORT+) - 60 Capsules *

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Description

NMN 1000+ (Previously NAD SUPPORT+) - 60 Capsules *NMN 1000+ Introducing a powerful, cutting edge supplement designed to support and enhance healthy NAD+ levelsvital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy

NMN 1000+

  • Introducing a powerful, cutting-edge supplement designed to support and enhance healthy NAD+ levels—vital for energy, cellular repair, and overall vitality. This innovative formula combines NMN (Nicotinamide Mononucleotide), a precursor to NAD+, with TMG(Trimethylglycine), which helps optimize methylation and support detoxification. Added Pterostilbene, a potent antioxidant, helps protect cells from oxidative stress while promoting healthy aging, and Apigenin, a natural flavonoid, further supports cellular health and cognitive function. Together, these ingredients work synergistically to elevate NAD+ levels, boost energy support, improve metabolic function, and promote longevity.

    Nicotinamide Mononucleotide: 1,000mg

    *This item may take longer to ship out*

    Key Benefits:

    • Boosts NAD+ Levels: Nicotinamide Mononucleotide is a direct precursor to NAD+, an essential molecule for energy production and cellular repair. By replenishing NAD+, NMN combats age-related declines in mitochondrial function and supports optimal metabolism.
    • Supports Longevity Pathways: Nicotinamide Mononucleotide activates sirtuins, enzymes that regulate DNA repair, inflammation control, and cellular health.
    • Enhances Physical and Cognitive Performance: Higher NAD+ levels improve endurance, recovery, and brain function.

    Scientific Evidence:

    • Studies show Nicotinamide Mononucleotide supplementation restores NAD+ levels, improving mitochondrial function and lifespan in animal models1
    • Human trials demonstrate Nicotinamide Mononucleotide's ability to enhance blood flow and muscle oxygenation2

    Trimethylglycine (TMG) (as Betaine Anhydrous): 500mg

    Key Benefits:

    • Supports Methylation Processes: TMG acts as a methyl donor, critical for processing homocysteine into methionine. This helps maintain healthy DNA and supports NMN's conversion into NAD+.
    • Protects Cells from Stress: TMG stabilizes proteins and cell membranes under osmotic stress, ensuring cellular integrity.
    • Supports Heart and Liver Health: Helps support homocysteine levels and cardiovascular risk factors.

    Scientific Evidence:

    • Research highlights TMG’s role in enhancing cellular methylation and metabolic efficiency3】【4】
    • TMG improves physical endurance and energy production in athletes5

    Pterostilbene: 50mg

    Key Benefits:

    • Antioxidant Powerhouse: A more bioavailable analog of resveratrol, pterostilbene neutralizes free radicals and protects against oxidative damage.
    • Activates Sirtuins: Supports longevity by enhancing sirtuin activity, which depends on NAD+.
    • Supports Cognitive Function: Protects brain cells from age-related decline, enhancing memory and focus.

    Scientific Evidence:

    • Studies suggest pterostilbene is more bioavailable and effective than resveratrol at promoting cellular health6】【7.
    • Pterostilbene has anti-inflammatory effects, supporting cardiovascular and brain health8.

    Apigenin: 50mg

    Key Benefits:

    • Inhibits CD38: Apigenin blocks CD38, an enzyme that depletes NAD+ levels, ensuring more NAD+ is available for critical cellular processes.
    • Anti-Inflammatory Properties: Supports chronic inflammation, a key driver of aging and age-related diseases.
    • Protects Against Oxidative Stress: Enhances cellular resilience by reducing oxidative damage to DNA, proteins, and lipids.

    Scientific Evidence:

    • Research confirms apigenin’s ability to inhibit CD38 and increase NAD+ availability9】【10.
    • Apigenin also shows neuroprotective effects, supporting healthy brain aging11

    The Synergy of Science

    By combining these four powerhouse ingredients,  supports NAD+ production through multiple pathways:

    • NMN: Directly replenishes NAD+ levels.
    • TMG: Facilitates Nicotinamide Mononucleotide metabolism via methylation.
    • Pterostilbene: Protects and enhances NAD+ and Sirtuin activity.
    • Apigenin: Reduces NAD+ depletion by inhibiting CD38.

    References

    1. Mills, K. F., et al. (2016). Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metabolism.
    2. Imai, S., & Guarente, L. (2014). NAD+ and sirtuins in aging and disease. Trends in Cell Biology.
    3. Craig, S. A. (2004). Betaine in human nutrition. American Journal of Clinical Nutrition.
    4. Zhao, X., et al. (2018). TMG alleviates mitochondrial stress by supporting methylation. Cell Reports.
    5. Hoffman, J. R., et al. (2009). Betaine supplementation and exercise performance. Journal of the International Society of Sports Nutrition.
    6. Remsberg, C. M., et al. (2008). Pharmacokinetics and metabolism of pterostilbene. Life Sciences.
    7. Rimando, A. M., et al. (2005). Pterostilbene as an antioxidant. Journal of Agricultural and Food Chemistry.
    8. McCormack, D., & McFadden, D. (2013). Pterostilbene and cancer. Antioxidants & Redox Signaling.
    9. Chini, C., et al. (2017). CD38 as a regulator of cellular NAD+ homeostasis. Nature Metabolism.
    10. Escande, C., et al. (2013). Apigenin and CD38 inhibition. Journal of Molecular Biology.
    11. Nabavi, S. F., et al. (2015). Neuroprotective effects of apigenin. Current Neurovascular Research.

    Additional Key References on  NAD

    • Song, Qin et al. “The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.” Advances in nutrition (Bethesda, Md.) vol. 14,6 (2023): 1416-1435. doi:10.1016/j.advnut.2023.08.008
    • Yi, Lin et al. “The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial.” GeroScience vol. 45,1 (2023): 29-43. doi:10.1007/s11357-022-00705-1
    • Soma, Mounica, and Satya Kumar Lalam. “The role of nicotinamide mononucleotide (NMN) in anti-aging, longevity, and its potential for treating chronic conditions.” Molecular biology reports vol. 49,10 (2022): 9737-9748. doi:10.1007/s11033-022-07459-1
    • Wei, Zisong et al. “Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?.” Current opinion in pharmacology vol. 60 (2021): 291-297. doi:10.1016/j.coph.2021.08.006
    • Rahman, Sajid Ur et al. “Role and Potential Mechanisms of Nicotinamide Mononucleotide in Aging.” Aging and disease vol. 15,2 565-583. 1 Apr. 2024, doi:10.14336/AD.2023.0519-1
    • Fukamizu, Yuichiro et al. “Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women.” Scientific reports vol. 12,1 14442. 24 Aug. 2022, doi:10.1038/s41598-022-18272-y
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4.2 ★★★★★
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Dolores Evans
Louisville, US
★★★★★ 5
Epic!!!!
Format: Kindle
Absolutely addicted from the first page. The twists and turns, world building and character development all come together for the perfect Omegaverse. And let's not forget that spice because knots are life and these are spectacular. Running for book #2 because that cliffhanger was torturous.
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Reviewed in the United States on August 17, 2024
A
Verified Purchase
Ashley Morgan
Carnegie, US
★★★★★ 5
ABSOLUTELY A MUST for Omegaverse Girls!!!
I ABSOLUTELY LOVE Jillian West and her books!!! I’m so happy I already bought book two and now I have to buy the others for the Assurance Security series!! Not gonna lie Val kind of annoyed me at the beginning but she grew on me!! Her men are chef’s kisses!!! Holt annoys me some but I can let it slide. I already bought part two so I’m going to be reading that in between work phone calls!!!! DON’T TELL MY BOSS 😂😂😂😂
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Reviewed in the United States on September 30, 2025
C
Verified Purchase
Carmen Alicea
Dallas, US
★★★★★ 4
Baby bumps and bodyguards
Format: Kindle
Dark, emotional, and unexpectedly tender, Not Ready is an omegaverse romance that delivers found family feels, fierce protectiveness, and a very pregnant heroine who refuses to break. Vale’s on the run from a stalker, but lands in the arms of three private security alphas, cue the swoony tension, fake marriage twist, and slow-burn heat. It’s a little gritty, a little soft, and a whole lot addictive. If you love protective alphas, high stakes, and heroines with quiet strength, this one’s a must-read.
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Reviewed in the United States on December 18, 2025
S
Verified Purchase
Shianne Whipple
Chelsea, US
★★★★★ 5
Strong Omegaverse Comfort and a Attention Grabbing Plot
Format: Kindle
Jillian West never misses when it comes to Omegaverse, and Not Ready is no exception. This story was the perfect blend of cozy comfort and emotional depth while still delivering a strong plot. Vale is such a powerful heroine, she is strong, capable, and determined but I love that she still allows her pack to love and take care of her. It’s that balance of independence and vulnerability that makes her so relatable. The relationship dynamics were amazing: Bishop is steadfast and completely head over heels, Mercy is skeptical but protective in his own way, and Holt is the hesitant one whose slow fall is so satisfying to watch unfold. The romance hits that sweet spot between insta-love and cautious build, keeping me hooked the entire way through. And that ending. Oh my god, the cliffhanger! I need the next book in this duet immediately.
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Reviewed in the United States on August 28, 2025
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NLB
Bozeman, US
★★★★★ 5
Interesting
Format: Kindle
So I will say I enjoyed the story, for sure had its moments where it dragged but it was a great story. I really liked that omegas picked their alphas/make the pack. Normally the Alphas make it and the omega fits in with them which is great but I enjoyed this new version where all the power basically went to the omega. It was a nice change of pace. I can admit some of the weird bedroom stuff with her being pregnant was odd, it’s really not hard to do stuff when pregnant (I know I’ve had two and it’s normal and even encouraged at the end especially if you want the baby out). But I like the story as a whole and will read the second, I do hope the next one isn’t dragged bc it stopped being action or tense after she met her alphas and I don’t think it was brought up or properly done when they tried to do it. More sweet after she left.
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Reviewed in the United States on November 11, 2024

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