SKU: 29314404098

Methylfolate - 5 mg, 60 Capsules

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Description

Methylfolate - 5 mg, 60 CapsulesFolate is a vital B vitamin that plays a key role in methylationa critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.* Why Quatrefolic? Quatrefolic is the glucosamine salt of (6S) 5 methyltetrahydrofolatethe

Folate is a vital B vitamin that plays a key role in methylation—a critical process for DNA synthesis, detoxification, neurotransmitter production, and cardiovascular health. Our formula delivers 5 mg of Quatrefolic®, the most advanced and bioavailable form of folate, designed to bypass genetic polymorphisms (such as MTHFR) that impair folic acid metabolism.*

Why Quatrefolic®?

Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate—the bioactive form of folate that the body uses directly, without requiring conversion. Unlike folic acid, which must go through multiple enzymatic steps to become active, Quatrefolic® is ready for immediate uptake and use at the cellular level.*

  • Clinically studied for enhanced bioavailability
  • Supports methylation pathways*
  • Supports healthy homocysteine balance*
  • Supports mood and cardiovascular health*
  • Essential for fetal development and reproductive health*

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Who It's For

This high-dose formula is ideal for individuals with increased folate needs or those with MTHFR gene variants who may have trouble converting folic acid to its usable form.*

How It Works

Folate is required to convert homocysteine into methionine—a process vital for cardiovascular and neurological function. It also supports the production of neurotransmitters like serotonin, dopamine, and norepinephrine, which influence mood and cognition.*

What Makes Ours Better?

  • Longevity Focused: We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*
  • Triple Lab Tested: Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.
  • Complete Transparency: In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body. 
  • USA Manufacturing Excellence: Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

References:

1 Bani Soheila, J Caring Sci 2013 
2 Mazza A. et al. Biol Regul Homeost Agents 2016
3 Rima Obeid R., Herrmann W. FEBS Letters 580, 2006
4 Stover Patrick, Curr Opin Biotechnol 2017
Seshadri S. at al. N Engl J Med 2002 
6 Bottiglieri T, J Neurol Neurosurg Psychiatry 2000 
7 Thaler C.J. 2014 
8 Stover PJ. Modern Nutrition in Health and Disease 2012
9 Tinelli C, Di Pino A Front. Nutr. 2019

Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 8,500 mcg DFE** (5 mg) 2,125%
* Daily Value (DV) **DFE (Dietary Folate Equivalent) 
REV. 10.24 
  • OTHER INGREDIENTS: Vegetable cellulose (capsule), cellulose.
  • SUGGESTED DAILY USE: Take one (1) capsule daily, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18 or are undergoing treatment for a
    medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 29314404098

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Gabriel King
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★★★★★ 5
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Color: Black, White, Navy Blue, Light Gray, Size: XX-Large
These shirt fits my body so perfectly! I’m 6’5” 310 pounds but I look 260 pounds. I sweat easily and I’m very sensitive to the material a piece of clothing is made of. This shirt is lightweight, extremely breathable, and feels like silk on the skin. It compliments and accentuates my contours to enhance my physique. I only tried on one and I’ve already ordered 12 more hehe. This is a cheat code.
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bigness
Omaha, US
★★★★★ 4
I Love the collar
Color: Black, White, Navy Blue, Wine Red, Size: Large
Great T-shirt. I can wear this casually with jeans or with a sports coat. The fabric is soft. There is no label in the collar, so you can wear it however you want.
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Reviewed in the United States on May 29, 2026
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Emel Djeipah
Dallas, US
★★★★★ 3
NOT a compression shirt
Color: Black, White, Navy Blue, Wine Red, Size: Large
These are well made with good quality material but are not what I was expecting given the picture. I am an XL and ordered a L because I wanted them to be tight (which they are not.) I decided not to return them because they are good shirts with a reasonable fit, but be advised these are not compression shirts.
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JIM D. MCGHEE
Los Angeles, US
★★★★★ 5
Ficerd high neck tee / I highly recommend...
Color: Black, White, Dark Gray, Light Gray, Size: Large
Great fit... Comfortable! Didn't shrink in the washer!! Didn't wrinkle up in the dryer!!!
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Amazon Customer
Houston, US
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Perfect for business casual
Color: Black, Light Gray, White, Brown, Size: Medium
Solid color shirts, cooling cloth as well. Great dinner or occasion shirt!
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Reviewed in the United States on April 15, 2026

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