SKU: 58123196165

Life Extension Senolytic Activator - with Quercetin, Fisetin 36 Vegetarian Capsules

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Life Extension Senolytic Activator - with Quercetin, Fisetin 36 Vegetarian CapsulesBrand: Life Extension Features: PROMOTE YOUTHFUL CELLULAR FUNCTION Cellular senescence is a natural part of aging when cells no longer function optimally. They can accumulate over time, affecting the daily function of your healthy cells. But new research indicates that black tea theaflavins and quercetin can make it easier for your body to manage senescent cells. EXPERIENCE A REJUVENATION Senolytic Activator combines black tea theaflavins, the plant

Brand: Life Extension

Features:

  • PROMOTE YOUTHFUL CELLULAR FUNCTION – Cellular senescence is a natural part of aging when cells no longer function optimally. They can accumulate over time, affecting the daily function of your healthy cells. But new research indicates that black tea theaflavins and quercetin can make it easier for your body to manage senescent cells.
  • EXPERIENCE A REJUVENATION - Senolytic Activator combines black tea theaflavins, the plant-derived flavonoid apigenin and ultra-absorbable forms of quercetin and fisetin to help manage senescent cells and promote systemic rejuvenation in your body.
  • TAKE JUST ONCE A WEEK - Whether you already take a number of daily supplements, or just welcome the convenience, Senolytic Activator only requires once-a-week dosing. It's easy to manage senescent cells, promote healthy cellular function and support longevity with Senolytic Activator.
  • INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves. The majority of our products are non-GMO, gluten-free, and manufactured in the USA—and a Certificate of Analysis is available for every product we produce.
  • LIVE YOUR HEALTHIEST LIFE - For over 40 years, we’ve been developing advanced, effective formulas made with the highest standards and based on the latest scientific findings. We believe the answers to a healthier, richer life are within reach, and that rigorous scientific research is the path to get us there. Our formulations are created using the ingredients and dosages used in the studies that inspired them, ensuring that maximum bioavailability and efficacy is achieved.

Part Number: 02301

Details: Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them. Senolytic compounds selectively target senescent cells.1 New research indicates that black tea theaflavins and quercetin target specific biological pathways, making it easier for the body to manage senescent cells. Theaflavins reduce senescent cell burden : Theaflavins are compounds derived from Camellia sinensis (tea plant). These compounds have widespread health benefits, supporting healthy cell division and healthy inflammatory response. New research indicates that theaflavins may be especially helpful for reducing senescent cell burden. In pre-clinical models, theaflavins helped powerfully inhibit the accumulation of particular cell senescence biomarkers. Quercetin promotes cellular health and more : Quercetin supports endothelial and cardiovascular health, promotes healthy immune function and more.7,8 The value of quercetin has been recognized for some time. But its potential to meaningfully impact whole body rejuvenation is just starting to be uncovered through its senolytic activity. The discovery that quercetin is a senolytic compound has drawn significant attention to this innovative approach to combat aging. Better absorption than standard types of quercetin : Standard quercetin is hard to absorb. But this formulation features our new quercetin phytosome, a phospholipid sphere that encases the quercetin, aiding in its absorption and making it up to 50 times more bioavailable. Easy-to-absorb fisetin to boost longevity at the cellular level : Fisetin is terrific for whole-body health. It’s a powerful senolytic compound, meaning it actively target senescent cells, the ones that no longer function optimally. Fisetin helps encourage the body’s natural pathways for clearing senescent cells, which allows healthy cells to flourish. Another important aspect of cellular longevity is sirtuin function. Sirtuin proteins keep your cells performing at their best—but sirtuin activity declines with age. Fisetin has been shown in preclinical studies to encourage youthful, healthy sirtuin function. But during digestion, much of fisetin is rapidly converted into other compounds by a process called conjugation. That’s why we protected fisetin by combining it with galactomannans, a type of fiber derived from fenugreek seed. Doing so makes it up to 25 times more readily available than standard fisetin. That means it circulates in your system longer and your body has more time to access fisetin’s many health benefits. Apigenin : Life Extension has identified apigenin, a natural flavonoid, as a powerful addition to our Senolytic Activator® formula. Quercetin and theaflavins from black tea target senescent cells, but not all of them. The remaining senescent cells create compounds known collectively as Senescence Associated Secretory Phenotype, or SASP.17 Apigenin helps inhibit remaining senescent cells from making SASP to support cellular and tissue health—a critical aspect of healthy aging. Convenient, once-weekly formula : For those who aren’t keen on adding another supplement to their regimen, here’s good news: Senolytic research indicates that intermittent dosing in pre-clinical studies is effective at supporting healthspan.4 So, Senolytic Activator® instructions call for taking just three vegetarian capsules, once a week. Manage senescent cells, promote healthy cellular function and support overall longevity with Senolytic Activator®.

EAN: 0737870230120

Package Dimensions: 4.2 x 3.3 x 0.8 inches

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SKU: 58123196165

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4.8 ★★★★★
Based on 18 reviews
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Natasha M.
Natrona Heights, US
★★★★★ 5
Crazy for her iguana!
Size: Medium/Large, Color: Illana the Iguana - Large, Size: Medium/Large, Color: Illana the Iguana - Large
Instant fav for my girl but looks like I'll be replacing often 🤪 she is a super chewer. She loves the soft vs hard combo on toys. Damage in the pic is within 10 mins. 😬😬😬 excellent quality
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
W
Verified Purchase
War317
San Leandro, US
★★★★★ 3
Foreign body risk for dinosaur dogs
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
My dog Bert had foreign body surgery 10 days ago because he swallowed a piece of a toy, so I was looking for something stronger, like for a tyrannosaurus rex. This toy had good reviews, so I bought it for him. In 25 minutes and he'd chomped a chunk of the blue water part off. Bought the toy around 8am, gave it to him around 8pm, and it was in the trash by 8:30pm. This toy is definitely NOT for super chewer tyrannosaurus rex dogs like Bert. But definitely IS a toy that is pretty sturdy and strong for dogs who don't have the bite force of a dinosaur.
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Reviewed in the United States on April 12, 2026
G
Verified Purchase
Gary Hugo
Louisville, US
★★★★★ 4
Definitely not indestructable
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
I have a 1-year-old toy fox terrier (Rocky, pictured). He has been chewing on this toy for seven months now; it is one of his favorites. He has been unable to seriously damage the "ocean" portion of this toy, but as you can see from the provided image, the sea serpent has not faired that well. It is missing its snout and smaller portions of the humps. My guess is that the advertiser images showing much larger dogs with "like new" versions of the toy are just that...NEW AND UNCHEWED. I have not had to clean up bits of this toy from my floor, so I assume Rocky has been swallowing them. My hope is that the yellow material of the serpent is not chemically dangerous when exposed to digestive fluids. Rocky easily destroys plush toys in a matter of days if not hours and, consumed pieces of a small microfiber blanket that he liked to toss around and play tug-of-war with (past tense as he destroyed it and has since been trashed after I began finding feces-stained undigested pieces of it lying around). Since this toy has survived seven months and has remained recognizable, I have to agree it is durable. Just beware, if my small toy fox terrier can damage the toy as pictured, expect your large breed chewer to do similar or worse damage. Also, the toy is very heavy! When Rocky drops it down a flight of stairs, it makes a MAJOR thud at the bottom, and sometimes makes me wonder if it might crack the large tile at the bottom. I cautiously recommend the product. Note the yellow frisbee in Rocky's picture. It is only a few months old and surprisingly has not suffered any chew damage despite substantial abuse. It appears to bend in the wind like a proverbial reed, evading damage by yielding to pressure.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on July 5, 2024
E
Verified Purchase
Elaina rice
Natrona Heights, US
★★★★★ 5
Dog loves it! For tough chewers for sure
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Dog absolutely loves it, he’s super rough on all of his toys they usually last about 10 minutes bore they are torn to shreds. It’s lasting through his chewing so I’m happy. It’s also super cute.
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Reviewed in the United States on April 9, 2026
M
Verified Purchase
miriana
Omaha, US
★★★★★ 5
Loch Yes
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Cute toy, dog really likes it. I had my doubts when I pulled it out, and honestly so did she, but the soft part bounces, so that got her going. We've had it for about a week. My dog is ~70 lbs and a moderate chewer, and this monster still gets regular play and is holding up well.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 18, 2026

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