SKU: 79664687882

NMN Pro 250™ Sustained Release - Uthever® NMN, 250 mg, 60 tabs - Living Machine™ - 3-Pack

Sale price$128.67 Regular price$142.97
Save 10%

Pay in installments of $35.74 with ShopPay, AfterPay and Klarna

Shipping Estimate
USA
  • USA
  • CAN

Ships within 48 hours · Estimated delivery Aug 16 - Aug 21

Promo Codes Available:

For Your Every Summer RSVP, with Code: SUMMER15

Description

NMN Pro 250™ Sustained Release - Uthever® NMN, 250 mg, 60 tabs - Living Machine™ - 3-PackCombat Aging, Improve Heart Health and Promote Muscle Strength NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression. Nicotinamide mononucleotide (NMN) is a derivative of the B vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+. NMN Pro 250 Sustained Release is

Combat Aging, Improve Heart Health and Promote Muscle Strength

  • NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
  • NMN Pro 250 Sustained Release is designed to slow and prolong NMN absorption, allowing a longer steady blood level concentration of the active ingredient. This enables NMN Pro 250 Sustained Release to be given at higher doses less frequently.

View Certificate of Analysis

Research Supported Benefits:

Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)

Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)

Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)

Supports Healthy Cognition. Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)

Supports Healthy Skin. In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)

References:

1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004

2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287

3. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287

4. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521

5. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238

6. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755

7. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5

8. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-

9. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013

10. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192

11. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060

12. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014

13. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 60
Amount Per Serving %DV
Uthever® β-Nicotinamide mononudeotide (NMN)
250 mg
† Daily Value not established
REV. 10.23
  • OTHER INGREDIENTS: Isomalt, modified pea protein, stearic acid, calcium palmitate, hydroxypropyl cellulose, pharmaceutical glaze.
  • SUGGESTED DAILY USE: Take 1 to 4 tablets in the morning, or as recommended by your healthcare practitioner.
  • NOTE: Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken.
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product. KEEP OUT OF REACH OF CHILDREN 
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.
  • NMN Pro 250 Sustained Release is designed to significantly enhance NAD+ production and absorption by raising NMN and NAD+ blood levels for up to 6 hours compared to approximately 6 minutes for non-stabilized NMN in animal studies. The gel barrier around the tablet effectively protects the NMN from harsh gastrointestinal acids and upon reaching the intestines can be released slowly.
  • Only Clincially-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.
  • Unique Delivery Method. NMN Pro 250 Sustained Release is designed to significantly enhance NAD+ production and absorption by raising NMN and NAD+ blood levels for up to 6 hours compared to approximately 6 minutes for non-stabilized NMN in animal studies. The gel barrier around the tablet effectively protects the NMN from harsh gastrointestinal acids and upon reaching the intestines can be released slowly.
  • Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.
  • Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
  • Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
Be Aware of Fake NMN: Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.
Shipping Notes
  • Free Standard Shipping on $100+ Orders to the USA.
  • Except Preorder products are shipped in 48 hours.
  • Delivery to the USA:
  1. Standard Shipping : 3-10 business days
  • If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
  • Please click here for more details>>> Return & Exchange Policy
SKU: 79664687882

Discover Niche Categories That Outsell

Top-Converting Item to Boost Your Average Order

4.1 ★★★★★
Based on 29 reviews
Sort
Highest Rating
Newest First
Oldest First
Product Reviews
A
Verified Purchase
Anel
Louisville, US
★★★★★ 5
Fav Chew Toy 🦴
Color: Blue, Color: Blue
My baby is half rottweiler and half doberman &’ he has a pretty strong grip when it comes to chew toys. But this one, it’s his favorite toy! He never leaves the house without it. It’s also really fun to add his favorite treats in there when’s he bored to keep him entertained! Not loud at all and will keep him from chewing on other things and not heavy as other rough chew toys!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 31, 2026
L
Verified Purchase
Love for Design
Grantham, US
★★★★★ 5
Great you made super well
Color: Blue Lil Snoop, Color: Blue Lil Snoop
This is such an awesome toy. It’s super durable strong bounces and a perfect size. We got the small. We got blue because our pup can see it. It allows for creativity and endless limits to what you can make for it to be a fun experience. It has a nice sized hole in the center which allows you to add treats and food. Pop it inward and it slightly if large enough prevents the treats from coming out super fast. The ball rolls bounces and they can grip it nicely. It is easy to clean The only thing I didn’t like was the way the plastic tabs were situated inside the toy as you just be careful you don’t allow it to drip inside and dog gets it. No noise just fun. Our 15lb Cavapoo loves it
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 17, 2026
K
Verified Purchase
Kay
Louisville, US
★★★★★ 3
No challenge once they figure it out once, or if they have a long nose
Color: Blue
The first time I used this with my 9 month old Shepard mix, it was great. We used about 1/3 cup of her kibble and added the Nook to make it harder. It kept her working for 20-30 minutes. However, now that she knows how to remove the Nook, and stick her snout into the opening and lick up the kibble, it lasts about 5 minutes, and is no longer a challenge. She still enjoys playing with this, even when it is empty, and hasn't it destroyed it yet, so for that 3 stars.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
J
Verified Purchase
Jaq
Lowell, US
★★★★★ 5
Buy it — it’ll be your dogs best friend!
Color: Orange
Best treat toy ever! In the beginning of 2025 I bought this for my 12yr old Alaskan Malamute who loves puzzles and brain games. She loved it and played with it every day. Sadly, she passed middle of this year. Now in December, I have purchased this toy again for my newly adopted 10 month Great Dane puppy. Again, it’s an absolute hit! My Dane eats very fast, so I actually use this as a way to break up her meals. I put about half her meal (freeze dried raw kibble) in her slow feeder bowl and fill this toy about two times to feed her the other half. Also, we are crate training and before I leave the house I put treats in this toy and leave it in the crate with her. She has bad separation anxiety, but this toy actually seems to help calm her down because she enjoys it so much. I have bought many treat toys — this one is supreme. It’s not too loud or too difficult for the dogs to play with. So far it has held up without being chewed apart. It’s good quality, great size (orange for large breeds) and honestly, worth every penny.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 12, 2025
M
Verified Purchase
m. h.
Houston, US
★★★★★ 5
Well made dog toy
Color: Blue
The snoops are great for our active labrador. He is a very aggressive chewer, and so far, has not destroyed a snoop yet. He has mulitples. They are a great size for filling with treats or kibble and they keep him engaged in the activity. He even likes to carry them when he does his zoomies sometimes. They are lightweight and sturdy, and the material is nice and flexible. Great toy / puzzle ball to have around for your pup!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 9, 2026

recommand products