Pay in installments of $166.62 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Aug 29 - Sep 3
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
MTBR-Tau243 (243-254) Recombinant Rabbit mAb (SDT-2032-13)Product Specification Host Rabbit Antigen MTBR Tau243 Synonyms microtubule binding region containing residue 243 Immunogen Synthetic Peptide Accession P10636 8 Clone Number SDT 2032 13 Antibody Type Recombinant mAb Isotype IgG Application ELISA, Competitive ELISA Reactivity Hu Cross Reactivity No cross reactivity against Tau peptide (aa242 254), it shows good binding ability with Tau peptide (aa243 254). Purification Protein A Concentration 2 mg ml
Product Specification
| Host | Rabbit |
| Antigen | MTBR-Tau243 |
| Synonyms | microtubule-binding region containing residue 243 |
| Immunogen | Synthetic Peptide |
| Accession | P10636-8 |
| Clone Number | SDT-2032-13 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | ELISA, Competitive ELISA |
| Reactivity | Hu |
| Cross Reactivity | No cross-reactivity against Tau peptide (aa242-254), it shows good binding ability with Tau peptide (aa243-254). |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Background
MTBR-Tau243 is a segment of the tau protein located within its microtubule-binding region (MTBR), specifically spanning the tau microtubule-binding region containing residue 243. This protein fragment has garnered significant attention as a specific biomarker for tau tangle pathology in Alzheimer's disease. Research has shown that MTBR-Tau243 levels in cerebrospinal fluid (CSF) and plasma are closely correlated with the presence and progression of neurofibrillary tangles, which are a hallmark of Alzheimer's. Unlike other tau biomarkers such as phosphorylated tau species, which are more related to amyloid plaques, MTBR-Tau243 is strongly associated with tau aggregates and cognitive impairment. Its detection in body fluids can help distinguish Alzheimer's disease from other neurodegenerative disorders and may serve as a valuable tool for monitoring disease progression and evaluating the efficacy of tau-targeted therapies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy