SKU: 12556336040

ALDH1A1 Rabbit Polyclonal Antibody

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Description

ALDH1A1 Rabbit Polyclonal AntibodyProduct Specification Host Rabbit Antigen ALDH1A1 Synonyms Aldehyde dehydrogenase 1A1; 3 deoxyglucosone dehydrogenase; ALDH E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic; Retinal dehydrogenase 1 (RALDH 1; RalDH1); ALDC; ALDH1 Immunogen Synthetic Peptide Location Cytoplasm Accession P00352 Antibody Type Polyclonal antibody Isotype IgG Application WB, IHC P Reactivity Hu, Ms Positive Sample HepG2, HT 29, A549,

Product Specification


Host Rabbit
Antigen ALDH1A1
Synonyms Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase; cytosolic; Retinal dehydrogenase 1 (RALDH 1; RalDH1); ALDC; ALDH1
Immunogen Synthetic Peptide
Location Cytoplasm
Accession P00352
Antibody Type Polyclonal antibody
Isotype IgG
Application WB, IHC-P
Reactivity Hu, Ms
Positive Sample HepG2, HT-29, A549, mouse liver, mouse lung
Purification Immunogen Affinity
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms
IHC-P 1:250 Hu, Ms

Background

Aldehyde dehydrogenase 1A1 (ALDH1A1) is an NADP-dependent enzyme belonging to the ALDH family, playing a crucial role in various physiological and toxicological processes. It is widely recognized as a marker for tumor-initiating cells and is involved in maintaining the stemness of tumor cells, promoting tumor angiogenesis and metastasis, and contributing to resistance against anticancer drugs. ALDH1A1 also lowers intracellular pH in breast cancer cells, suppressing antitumor immunity and fostering cancer progression. Recent studies have shown that ALDH1A1 upregulates ZBTB7B, a transcription factor that promotes glycolysis in tumor cells, leading to increased lactate production and immune evasion. This highlights ALDH1A1's potential as a therapeutic target for cancer immunotherapy.

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SKU: 12556336040

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4.8 ★★★★★
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Amazon Customer
Draper, US
★★★★★ 5
Gentle vibrations and rolling
My sweet old man dog didnt know what to think of this at first. We introduced it to him without turning it on at first, like a regular ball. That was fine, he was good with that and he liked to go chasing it (its heavy because its mechanical so I wouldnt throw it, a light toss/roll is how we started). After we played that way a while we turned it on. At first he was confused as to why his toy was chasing him. It mostly vibrates and bops around a bit. But then my pup started chasing it and kicking it around like a little soccer ball and he LOVED THAT. A charge lasts quite a while too and if he doesnt play with it in for a few minutes it goes to sleep so its not just bouncing constantly and driving me crazy. My pup likes it and it gives me a rest from the constant throwing so I'm happy!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 7, 2026
V
Vigil family
Alexandria, US
★★★★★ 5
Keeps My Dog Entertained for Hours!
This auto-rolling dog ball has been a total game changer for keeping my dog busy and active! The second I turned it on, my dog was instantly curious and started chasing it all over the house. It moves and rotates in a really fun, unpredictable way that keeps their attention much longer than regular toys. I love that it helps with boredom relief, especially on days when we can’t get outside as much. It’s perfect for indoor play but also works great outside too. The material feels durable and holds up well against chewing, which is a must for my pup. The USB rechargeable feature is super convenient—no constantly replacing batteries—and it holds a charge long enough for multiple play sessions. I also appreciate that it’s easy to clean and has some water resistance, so I don’t have to worry too much about slobber or a little outdoor use. Overall, this is a fun, interactive toy that actually keeps dogs engaged and moving. Highly recommend for anyone with an energetic or easily bored pup!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 5, 2026
H
Verified Purchase
Homesick Martian
Lowell, US
★★★★★ 5
Great toy!
Pattern Name: Carrot
"Dog toys by Dole? The banana people??" Yep, me too. My dog loves this toy. The plastic piece is a great texture for chewing. The stuffy is small enough for most puppies and will grow to medium sized dogs. The green of the carrot crinkles and they both wash up good. The stuffy has been through the wash many times. Good quality, durable toys.
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Reviewed in the United States on June 4, 2026
L
Lara
Fort Morgan, US
★★★★★ 4
The plastic is easy to chew through
Pattern Name: Carrot, Pattern Name: Carrot
Taking off one star on what would otherwise be a five-star product because dogs can chew off small plastic pieces fairly easily. Other than that, my dogs went wild for this toy and loved playing with it and chewing on it for hours. If your dog isn’t a heavy chewer, I’d definitely recommend it. Otherwise, close supervision is strongly advised. That said, I really like the other materials used, the crinkly fabric carrot top is especially fun and engaging for dogs. Overall, I think this would be an even better product if the material for the carrot base were made from a harder, more durable plastic.
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Reviewed in the United States on May 20, 2026
C
Verified Purchase
Carolyn E. Haaga
Belleville, US
★★★★★ 5
MinPin puppy approved!
Pattern Name: Strawberry
MinPin puppy approved! This is a great toy to occupy busy furbabies.
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Reviewed in the United States on April 24, 2026

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