SKU: 13006788730

Alexa Fluor® 647 Rat Anti-Human XCR1 Antibody (S-3294)

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Ships within 48 hours · Estimated delivery Aug 30 - Sep 4

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Description

Alexa Fluor® 647 Rat Anti-Human XCR1 Antibody (S-3294)Product Specification Host Rat Antigen XCR1 Synonyms Chemokine XC receptor 1; G protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1; CCXCR1; GPR5 Location Cell membrane Accession P46094 Clone Number S 3294 Antibody Type Rat mAb Isotype IgG2a,k Application FCM Reactivity Hu Positive Sample Human PBMC Purification Protein G Concentration 0. 2 mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 1% BSA,

Product Specification


Host Rat
Antigen XCR1
Synonyms Chemokine XC receptor 1; G-protein coupled receptor 5; Lymphotactin receptor; XC chemokine receptor 1; CCXCR1; GPR5
Location Cell membrane
Accession P46094
Clone Number S-3294
Antibody Type Rat mAb
Isotype IgG2a,k
Application FCM
Reactivity Hu
Positive Sample Human PBMC
Purification Protein G
Concentration 0.2 mg/ml
Conjugation Alexa Fluor® 647
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Hu

Background

XCR1 is a conserved, 7-transmembrane G-protein-coupled receptor selectively expressed on CD8α⁺ and CD103⁺ classical dendritic cells; its exclusive ligand XCL1 is secreted by activated CD8⁺ T and NK cells, forming a chemotactic feedback loop that recruits antigen-loaded DCs into lymphoid tissue and optimizes cross-presentation, Th1 cytotoxicity and antiviral/antitumor immunity, making the XCR1–XCL1 axis an emerging target for cancer immunotherapy and vaccine adjuvant design.

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Exchange/Return Notes
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SKU: 13006788730

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Reviewed in the United States on October 31, 2025

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