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Description
Glypican-3 Recombinant Rabbit mAb,PBS Only (SDT-R032)Product Specification Host Rabbit Antigen Glypican 3 Synonyms GTR2 2, MXR7GPC3OCI5 Immunogen N A Location Cytoplasm, Cell membrane Accession P51654 Clone Number SDT R032 Antibody Type Rabbit mAb Application WB, IHC P, ICC, FCM, IP, IF Reactivity Hu Purification Protein A Concentration 1 mg ml Physical Appearance Liquid Storage Buffer PBS Stability & Storage 12 months from date of receipt, 4C as supplied Dilution application dilution species WB 1: 1000
Product Specification
| Host | Rabbit |
| Antigen | Glypican-3 |
| Synonyms | GTR2-2, MXR7，GPC3，OCI5 |
| Immunogen | N/A |
| Location | Cytoplasm, Cell membrane |
| Accession | P51654 |
| Clone Number | SDT-R032 |
| Antibody Type | Rabbit mAb |
| Application | WB, IHC-P, ICC, FCM, IP, IF |
| Reactivity | Hu |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt, 4°C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500 | |
| ICC | 1:500 | |
| FCM | 1:500 | |
| IP | 1:25 | |
| IF | 1:200 |
Background
Glypican-3 (GPC3) is a cell-surface glyco phosphatidylinositol (GPI)-anchored protein that belongs to the heparan sulfate (HS) proteoglycan family, which plays important roles in cell growth, differentiation and migration. Many studies have shown that GPC3 is highly expressed in HCC, while its expression is absent in most nonmalignant adult tissues. GPC3 is currently used as an informative immunohistochemical biomarker for HCC, and it is believed to be an attractive target for HCC therapy.
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