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Description
BDNF Protein, Human/Mouse/RatProduct Specification Species Human, Mouse, Rat Synonyms Neurotrophic factor BDNF precursor form,proBDNF, Alternative names,Abrineurin,Brain derived neurotrophic factor Accession P23560 Amino Acid Sequence His129 Arg247 Expression System E. coli Molecular Weight 13 KDa Purity >95% by SDS PAGE Endotoxin <0. 01EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer 20mM PB, 400mM NaCl, pH 7. 2. Reconstitution
Product Specification
| Species | Human, Mouse, Rat |
| Synonyms | Neurotrophic factor BDNF precursor form,proBDNF, Alternative names,Abrineurin,Brain-derived neurotrophic factor |
| Accession | P23560 |
| Amino Acid Sequence | His129-Arg247 |
| Expression System | E.coli |
| Molecular Weight | 13 KDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.01EU/μg |
| Conjugation | Unconjugated |
| Tag | No Tag |
| Physical Appearance | Lyophilized powder |
| Storage Buffer | 20mM PB, 400mM NaCl, pH 7.2. |
| Reconstitution |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Stability & Storage |
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Background
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
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